Dual role of fibroblasts educated by tumour in cancer behavior and therapeutic perspectives
Tumours are complex systems with dynamic interactions between tumour cells, non-tumour
cells, and extracellular components that comprise the tumour microenvironment (TME). The …
cells, and extracellular components that comprise the tumour microenvironment (TME). The …
Recent advances in tumor microenvironment-targeted nanomedicine delivery approaches to overcome limitations of immune checkpoint blockade-based …
Cancer immunotherapy has revolutionized the standard of care for solid tumors in multiple
disease sites. In light of this, immune checkpoint blockade, directly interfering with various …
disease sites. In light of this, immune checkpoint blockade, directly interfering with various …
Immune checkpoint inhibitors in urothelial cancer: recent updates and future outlook
D Gopalakrishnan, VS Koshkin… - … and clinical risk …, 2018 - Taylor & Francis
Bladder cancer is the sixth most common cancer in the US and most tumors have urothelial
(transitional cell) histology. Platinum-based chemotherapy has long been the standard of …
(transitional cell) histology. Platinum-based chemotherapy has long been the standard of …
The changing landscape of systemic treatment of advanced hepatocellular carcinoma: new targeted agents and immunotherapies
Hepatocellular carcinoma (HCC) is one of the most common and deadliest cancers
worldwide with a rising incidence in the Western world. HCCs are characterized by high …
worldwide with a rising incidence in the Western world. HCCs are characterized by high …
Cuprotosis patterns are associated with tumor mutation burden and immune landscape in lung adenocarcinoma
T Liu, L Cai, H Hua, X Jiang, X Xu, T Zhang… - Journal of …, 2022 - Wiley Online Library
Background. The association involving cuprotosis, molecular subtype, and specific immune
cell groups in the tumor microenvironment has been focused on by more recent studies. In …
cell groups in the tumor microenvironment has been focused on by more recent studies. In …
[HTML][HTML] Comprehensive analysis of immune subtype characterization on identification of potential cells and drugs to predict response to immune checkpoint inhibitors …
G Lai, B Xie, C Zhang, X Zhong, J Deng, K Li, H Liu… - Genes & …, 2024 - Elsevier
Immunosubtyping enables the segregation of immune responders from non-responders.
However, numerous studies failed to focus on the integration of cellular heterogeneity and …
However, numerous studies failed to focus on the integration of cellular heterogeneity and …
[HTML][HTML] Matrix Metalloproteinase-9 is associated with tumor microenvironment remodeling of bladder cancer
F Fang, T Wu, M Wang, W Li, Z You, M Chen… - Biology …, 2025 - pmc.ncbi.nlm.nih.gov
Tumor microenvironment (TME) takes an essential part in the bladder cancer progression,
which is associated with intercellular cross-talk between stroma cells and cancer. We aimed …
which is associated with intercellular cross-talk between stroma cells and cancer. We aimed …
Prognostic value of programmed death-ligand 1 status in Japanese patients with renal cell carcinoma
M Uemura, N Nakaigawa, N Sassa… - International Journal of …, 2021 - Springer
Background Programmed death-ligand 1 (PD-L1) positivity is associated with poor
prognosis in renal cell carcinoma (RCC). Because the prognostic impact and effect of …
prognosis in renal cell carcinoma (RCC). Because the prognostic impact and effect of …
Expansion and Characterization of Tumour Derived T Lymphocytes from Undifferentiated Pleomorphic Sarcoma
JHK Chen - 2022 - search.proquest.com
Sarcoma is a group of rare bone and soft tissue tumours with over 50 distinct subtypes.
Survival rate of metastatic sarcoma is poor due to the lack of efficacious treatments and …
Survival rate of metastatic sarcoma is poor due to the lack of efficacious treatments and …