Alternative splicing as a source of phenotypic diversity
A major goal of evolutionary genetics is to understand the genetic processes that give rise to
phenotypic diversity in multicellular organisms. Alternative splicing generates multiple …
phenotypic diversity in multicellular organisms. Alternative splicing generates multiple …
The DNA methyltransferase family: a versatile toolkit for epigenetic regulation
F Lyko - Nature Reviews Genetics, 2018 - nature.com
The DNA methyltransferase (DNMT) family comprises a conserved set of DNA-modifying
enzymes that have a central role in epigenetic gene regulation. Recent studies have shown …
enzymes that have a central role in epigenetic gene regulation. Recent studies have shown …
Comparison of whole-genome bisulfite sequencing library preparation strategies identifies sources of biases affecting DNA methylation data
Background Whole-genome bisulfite sequencing (WGBS) is becoming an increasingly
accessible technique, used widely for both fundamental and disease-oriented research …
accessible technique, used widely for both fundamental and disease-oriented research …
Evolution of DNA methylation across insects
DNA methylation contributes to gene and transcriptional regulation in eukaryotes, and
therefore has been hypothesized to facilitate the evolution of plastic traits such as sociality in …
therefore has been hypothesized to facilitate the evolution of plastic traits such as sociality in …
[HTML][HTML] The locust genome provides insight into swarm formation and long-distance flight
Locusts are one of the world's most destructive agricultural pests and represent a useful
model system in entomology. Here we present a draft 6.5 Gb genome sequence of Locusta …
model system in entomology. Here we present a draft 6.5 Gb genome sequence of Locusta …
Epigenetic modification and inheritance in sexual reversal of fish
Environmental sex determination (ESD) occurs in divergent, phylogenetically unrelated taxa,
and in some species, co-occurs with genetic sex determination (GSD) mechanisms …
and in some species, co-occurs with genetic sex determination (GSD) mechanisms …
Enhancer DNA methylation: implications for gene regulation
A Angeloni, O Bogdanovic - Essays in biochemistry, 2019 - portlandpress.com
DNA methylation involves the addition of a methyl group to the fifth carbon of the pyrimidine
cytosine ring (5-methylcytosine, 5mC). 5mC is widespread in vertebrate genomes where it is …
cytosine ring (5-methylcytosine, 5mC). 5mC is widespread in vertebrate genomes where it is …
Epigenetics, plasticity, and evolution: How do we link epigenetic change to phenotype?
EJ Duncan, PD Gluckman… - Journal of Experimental …, 2014 - Wiley Online Library
Epigenetic mechanisms are proposed as an important way in which the genome responds
to the environment. Epigenetic marks, including DNA methylation and Histone modifications …
to the environment. Epigenetic marks, including DNA methylation and Histone modifications …
The emergence of the brain non-CpG methylation system in vertebrates
Mammalian brains feature exceptionally high levels of non-CpG DNA methylation alongside
the canonical form of CpG methylation. Non-CpG methylation plays a critical regulatory role …
the canonical form of CpG methylation. Non-CpG methylation plays a critical regulatory role …
Genomics of developmental plasticity in animals
E Lafuente, P Beldade - Frontiers in genetics, 2019 - frontiersin.org
Developmental plasticity refers to the property by which the same genotype produces
distinct phenotypes depending on the environmental conditions under which development …
distinct phenotypes depending on the environmental conditions under which development …