Sex-specific placental responses in fetal development

CS Rosenfeld - Endocrinology, 2015 - academic.oup.com
The placenta is an ephemeral but critical organ for the survival of all eutherian mammals
and marsupials. It is the primary messenger system between the mother and fetus, where …

The role of epigenetics in placental development and the etiology of preeclampsia

C Apicella, CSM Ruano, C Méhats, F Miralles… - International journal of …, 2019 - mdpi.com
In this review, we comprehensively present the function of epigenetic regulations in normal
placental development as well as in a prominent disease of placental origin, preeclampsia …

Role of microRNAs in embryo implantation

J Liang, S Wang, Z Wang - Reproductive Biology and Endocrinology, 2017 - Springer
Failure of embryo implantation is a major limiting factor in early pregnancy and assisted
reproduction. Determinants of implantation include the embryo viability, the endometrial …

MicroRNAs in placental health and disease

JF Mouillet, Y Ouyang, CB Coyne… - American journal of …, 2015 - Elsevier
MicroRNAs (miRNAs) constitute a large family of small noncoding RNAs that are encoded
by the genomes of most organisms. They regulate gene expression through …

Sex differences in innate and adaptive immunity impact fetal, placental, and maternal health

KJ Baines, RC West - Biology of reproduction, 2023 - academic.oup.com
The differences between males and females begin shortly after birth, continue throughout
prenatal development, and eventually extend into childhood and adult life. Male embryos …

MicroRNAs in the regulation of endometrial receptivity for embryo implantation

M Shekibi, S Heng, G Nie - International journal of molecular sciences, 2022 - mdpi.com
Development of endometrial receptivity is crucial for successful embryo implantation and
pregnancy initiation. Understanding the molecular regulation underpinning endometrial …

Circulating extracellular vesicles in healthy and pathological pregnancies: A scoping review of methodology, rigour and results

MVC Barnes, P Pantazi, B Holder - Journal of Extracellular …, 2023 - Wiley Online Library
Extracellular vesicles (EVs) play a crucial role in pregnancy, revealed by the presence of
placental‐derived EVs in maternal blood, their in vitro functionality, and their altered cargo in …

Epigenetic processes during preeclampsia and effects on fetal development and chronic health

UM Ashraf, DL Hall, AZ Rawls, BT Alexander - Clinical Science, 2021 - portlandpress.com
Preeclampsia (PE), the leading cause of maternal and fetal morbidity and mortality, is
associated with poor fetal growth, intrauterine growth restriction (IUGR) and low birth weight …

ETMR: a tumor entity in its infancy

S Lambo, K von Hoff, A Korshunov, SM Pfister… - Acta …, 2020 - Springer
Abstract Embryonal tumor with Multilayered Rosettes (ETMR) is a relatively rare but typically
deadly type of brain tumor that occurs mostly in infants. Since the discovery of the …

Oxygen tension regulates the miRNA profile and bioactivity of exosomes released from extravillous trophoblast cells–liquid biopsies for monitoring complications of …

G Truong, D Guanzon, V Kinhal, O Elfeky, A Lai… - PloS one, 2017 - journals.plos.org
Our understanding of how cells communicate has undergone a paradigm shift since the
recent recognition of the role of exosomes in intercellular signaling. In this study, we …