Combined approaches for increasing fetal hemoglobin (HbF) and de novo production of adult hemoglobin (HbA) in erythroid cells from β-thalassemia patients …
Genome editing (GE) is one of the most efficient and useful molecular approaches to correct
the effects of gene mutations in hereditary monogenetic diseases, including β-thalassemia …
the effects of gene mutations in hereditary monogenetic diseases, including β-thalassemia …
Pharmacogenomics of Drugs Used in β-Thalassemia and Sickle-Cell Disease: From Basic Research to Clinical Applications
In this short review we have presented and discussed studies on pharmacogenomics (also
termed pharmacogenetics) of the drugs employed in the treatment of β-thalassemia or Sickle …
termed pharmacogenetics) of the drugs employed in the treatment of β-thalassemia or Sickle …
Saracatinib prompts hemin-induced K562 erythroid differentiation but suppresses erythropoiesis of hematopoietic stem cells
L Ding, D Chen, Y Li, Y Xie, X Sun, D Wang - Human Cell, 2024 - Springer
Human myeloid leukemia cells (such as K562) could be used for the study of erythropoiesis,
and mature erythroid markers and globins could be induced during leukemia cell …
and mature erythroid markers and globins could be induced during leukemia cell …
[PDF][PDF] Alessia Finotti1, 2* and Roberto Gambari1, 2
The β-thalassemias are a genetically heterogenous group of hereditary hematological
diseases caused by hundreds of mutations of the adult β-globin gene, leading to low or …
diseases caused by hundreds of mutations of the adult β-globin gene, leading to low or …
[PDF][PDF] Quantitative Analysis of γ-Globin Gene Expression in Human Erythroleukaemic K562 Cells Treated with Theobroma cacao Bark Ethanolic Extract
Therapeutic reactivation of foetal haemoglobin (HbF) can alleviate clinical complications
associated with sickle cell anaemia (SCA), a severe monogenic disorder that is prevalent in …
associated with sickle cell anaemia (SCA), a severe monogenic disorder that is prevalent in …