In recent years, tumor immunotherapy has made significant progress. However, tumor
immunotherapy, particularly immune checkpoint inhibitors (eg, PD-1/PD-L1 inhibitors) …

Cigarette smoking is the leading cause of preventable death worldwide. It causes chronic
lung disease and predisposes individuals to acute lung injury and pulmonary infection …

The codependency of cholesterol metabolism sustains the malignant progression of
glioblastoma (GBM) and effective therapeutics remain scarce. In orthotopic GBM models in …

Lung cancer is a leading cause of cancer-related deaths worldwide. About 10–30% of
patients with non-small cell lung cancer (NSCLC) harbor mutations of the EGFR gene. The …

Multiresponsive adjuvant nanoparticles (RMmAGL) are fabricated to perform tumor‐specific
photothermal therapy while regulating the behavior of tumor‐associated immune cells for …

Cold tumor microenvironment (TME) marked with low effector T cell infiltration leads to weak
response to immune checkpoint inhibitor (ICI) treatment. Thus, switching cold to hot TME is …

Tumor-associated macrophages (TAMs) are among the main contributors to immune
suppression in the tumor microenvironment, however, TAM depletion strategies have …

Background Tumor-associated macrophages (TAMs) play a key immunosuppressive role
that limits the ability of the immune system to fight cancer and hinder the antitumoral efficacy …

Hepatocellular carcinoma (HCC) is one of the most common malignant tumors worldwide,
with high rates of recurrence and death. Surgical resection and ablation therapy have limited …

The Immunoscore is a method to quantify the immune cell infiltration within cancers to
predict the disease prognosis. Previous immune profiling approaches relied on limited …