Normal maintenance of human motivation depends on the integrity of subcortical structures
that link the prefrontal cortex with the limbic system. Structural and functional disruption of …

Increased rostral anterior cingulate cortex (rACC) activity has emerged as a promising
predictor of treatment response in depression, but neither the reliability of this relationship …

Was wissen wir heute über die neuronalen Strukturen und Prozesse, die normalem und
gestörtem Erleben und Verhalten zu Grunde liegen? Was wissen wir über die neuronalen …

OBJECTIVE: Theories of human behavior from Plato to Freud have repeatedly emphasized
links between emotion and reason, a relationship now commonly attributed to pathways …

To date, there has been little investigation of the neurobiological basis of emotion
processing abnormalities in psychiatric populations. We have previously discussed two …

Brain areas implicated in the stress response include the amygdala, hippocampus, and
prefrontal cortex. Traumatic stress can be associated with lasting changes in these brain …

▪ Abstract Depression is a disorder of the representation and regulation of mood and
emotion. The circuitry underlying the representation and regulation of normal emotion and …

Depression is one of the most prevalent and debilitating of the psychiatric disorders. Studies
have shown that cognitive therapy is as efficacious as antidepressant medication at treating …

The limited success of genetic studies of major depression has raised questions concerning
the definition of genetically relevant phenotypes. This paper presents strategies to improve …

Background Functional imaging studies of major depressive disorder demonstrate response-
specific regional changes following various modes of antidepressant treatment. Objective To …