Probing neural tissues at small scales: Recent progress of oscillating gradient spin echo (OGSE) neuroimaging in humans

J Xu - Journal of neuroscience methods, 2021 - Elsevier
The detection sensitivity of diffusion MRI (dMRI) is dependent on diffusion times. A shorter
diffusion time can increase the sensitivity to smaller length scales. However, the …

Magnetic resonance imaging of mean cell size in human breast tumors

J Xu, X Jiang, H Li, LR Arlinghaus… - Magnetic resonance …, 2020 - Wiley Online Library
Purpose Cell size is a fundamental characteristic of all tissues, and changes in cell size in
cancer reflect tumor status and response to treatments, such as apoptosis and cell‐cycle …

MR cell size imaging with temporal diffusion spectroscopy

X Jiang, H Li, SP Devan, JC Gore, J Xu - Magnetic resonance imaging, 2021 - Elsevier
Cytological features such as cell size and intracellular morphology provide fundamental
information on cell status and hence may provide specific information on changes that arise …

Promising renoprotective effect of gold nanoparticles and dapagliflozin in diabetic nephropathy via targeting miR‐192 and miR‐21

SM Al‐Tantawy, SM Eraky… - Journal of Biochemical …, 2023 - Wiley Online Library
Diabetic nephropathy (DN) is a worldwide issue that eventually leads to end‐stage renal
failure, with limited therapeutic options. Prior research has revealed that gold nanoparticles …

[HTML][HTML] MRI of tumor T cell infiltration in response to checkpoint inhibitor therapy

X Jiang, S Dudzinski, KE Beckermann… - … for immunotherapy of …, 2020 - ncbi.nlm.nih.gov
Background Immune checkpoint inhibitors, the most widespread class of immunotherapies,
have demonstrated unique response patterns that are not always adequately captured by …

Revealing tumor microstructure with oscillating diffusion encoding MRI in pre‐surgical and post‐treatment glioma patients

A Zhu, R Shih, RY Huang, JK DeMarco… - Magnetic resonance …, 2023 - Wiley Online Library
Purpose We hypothesized that the time‐dependent diffusivity at short diffusion times, as
measured by oscillating gradient spin echo (OGSE) diffusion MRI, can characterize tissue …

Improving MR cell size imaging by inclusion of transcytolemmal water exchange

X Jiang, SP Devan, J Xie, JC Gore, J Xu - NMR in Biomedicine, 2022 - Wiley Online Library
The goal of the current study is to include transcytolemmal water exchange in MR cell size
imaging using the IMPULSED model for more accurate characterization of tissue cellular …

MRI‐cytometry: mapping nonparametric cell size distributions using diffusion MRI

J Xu, X Jiang, SP Devan, LR Arlinghaus… - Magnetic resonance …, 2021 - Wiley Online Library
Purpose This report introduces and validates a new diffusion MRI‐based method, termed
MRI‐cytometry, which can noninvasively map intravoxel, nonparametric cell size …

Mapping hepatocyte size in vivo using temporal diffusion spectroscopy MRI

X Jiang, J Xu, JC Gore - Magnetic Resonance in Medicine, 2020 - Wiley Online Library
Purpose The goal of this study is to implement a noninvasive method for in vivo mapping of
hepatocyte size. This method will have a broad range of clinical and preclinical applications …

Diffusion‐prepared 3D gradient spin‐echo sequence for improved oscillating gradient diffusion MRI

D Wu, D Liu, YC Hsu, H Li, Y Sun… - Magnetic resonance …, 2021 - Wiley Online Library
Purpose Oscillating gradient (OG) enables the access of short diffusion times for time‐
dependent diffusion MRI (dMRI); however, it poses several technical challenges for clinical …