Systemic complications of acromegaly and the impact of the current treatment landscape: an update

MR Gadelha, L Kasuki, DST Lim… - Endocrine reviews, 2019 - academic.oup.com
Acromegaly is a chronic systemic disease with many complications and is associated with
increased mortality when not adequately treated. Substantial advances in acromegaly …

Type 2 diabetes mellitus is associated with increased risk of sarcopenia: a systematic review and meta-analysis

P Anagnostis, NK Gkekas, C Achilla… - Calcified tissue …, 2020 - Springer
Diabetes mellitus (DM) is associated with an increased risk of fractures, mainly due to
impaired bone architecture and microvascular complications. Whether DM is also …

Menopause and diabetes: EMAS clinical guide

R Slopien, E Wender-Ozegowska… - Maturitas, 2018 - Elsevier
Introduction Whether menopause increases the risk of type 2 diabetes mellitus (T2DM)
independently of ageing has been a matter of debate. Controversy also exists about the …

Diabetes and aging: from treatment goals to pharmacologic therapy

M Longo, G Bellastella, MI Maiorino, JJ Meier… - Frontiers in …, 2019 - frontiersin.org
Diabetes is becoming one of the most widespread health burning problems in the elderly.
Worldwide prevalence of diabetes among subjects over 65 years was 123 million in 2017, a …

Vitamin D deficiency, osteoporosis and effect on autoimmune diseases and hematopoiesis: a review

M De Martinis, A Allegra, MM Sirufo, A Tonacci… - International journal of …, 2021 - mdpi.com
Vitamin D (VD) is essential for bone homeostasis, but it is also involved in pleiotropic effects
on various organs and tissues. In adults, VD deficiency can cause or exacerbate …

The interplay between diabetes mellitus and menopause: clinical implications

I Lambrinoudaki, SA Paschou, E Armeni… - Nature Reviews …, 2022 - nature.com
The menopausal transition is an impactful period in women's lives, when the risk of
cardiovascular disease is accelerated. Similarly, diabetes mellitus profoundly impacts …

Diabetes and bone fragility

C Romero-Díaz, D Duarte-Montero… - Diabetes Therapy, 2021 - Springer
Diabetes is a highly prevalent disease with complications that impact most bodily systems.
However, the impact of diabetes on bone health is frequently ignored or underestimated …

Effects of anti-diabetic drugs on fracture risk: a systematic review and network meta-analysis

YS Zhang, YD Zheng, Y Yuan, SC Chen… - Frontiers in …, 2021 - frontiersin.org
Purpose Available data on the effects of anti-diabetic drugs on fracture risk are contradictory.
Therefore, our study aimed to analyze all available data on the effects of anti-diabetic drugs …

Gut microbiota and bone metabolism

L Lu, X Chen, Y Liu, X Yu - The FASEB Journal, 2021 - Wiley Online Library
Osteoporosis is the most common metabolic skeletal disease. It is characterized by the
deterioration of the skeletal microarchitecture and bone loss, leading to ostealgia, and even …

Role of advanced glycation end-products and oxidative stress in type-2-diabetes-induced bone fragility and implications on fracture risk stratification

G Cavati, F Pirrotta, D Merlotti, E Ceccarelli… - Antioxidants, 2023 - mdpi.com
Type 2 diabetes (T2D) and osteoporosis (OP) are major causes of morbidity and mortality
that have arelevant health and economic burden. Recent epidemiological evidence …