Nature as a source and inspiration for human monoamine oxidase B (hMAO-B) inhibition: A review of the recent advances in chemical modification of natural …

F Melfi, S Carradori, A Angeli… - Expert Opinion on Drug …, 2023 - Taylor & Francis
Introduction Over the past 5 years, we have witnessed intense research activity about the
biological potential of natural products (NPs) as human monoamine oxidase B (hMAO-B) …

Advances in chalcone derivatives: Unravelling their anticancer potential through structure-activity studies

KA Sheikh, A Gupta, M Umar, R Ali… - Journal of Molecular …, 2024 - Elsevier
Cancer continues to be a global health challenge, thereby necessitating the evolution of
innovative therapeutic strategies. The synthesis of chalcone derivatives has garnered …

A Brief Review on the Synthesis of 4H‐Chromene‐Embedded Heterocycles

KN Sharon, P Padmaja, PN Reddy - ChemistrySelect, 2024 - Wiley Online Library
Chromenes are an essential class of oxygen‐containing heterocyclic compounds with
intriguing biological activity. It is an important moiety for the discovery of new drug …

A metal-free strategy to construct fluoroalkyl–olefin linkages using fluoroalkanes

K Chakrabarti, MMW Wolfe, S Guo, JW Tucker… - Chemical …, 2024 - pubs.rsc.org
We present a metal-free strategy to access fluoroalkyl–olefin linkages from fluoroalkane
precursors and vinyl-pinacol boronic ester (BPin) reagents. This reaction sequence is …

Synthesis and Characterization of a New Class of Chromene-Azo Sulfonamide Hybrids as Promising Anticancer Candidates with the Exploration of Their EGFR, h …

FF Alblewi, MH Alsehli, ZM Hritani… - International Journal of …, 2023 - mdpi.com
In this study, novel selective antitumor compounds were synthesized based on their
fundamental pharmacophoric prerequisites associated with EGFR inhibitors. A molecular …

Catalyst-Controlled Divergent Synthesis of 2H-Chromenes via [3 + 3] Annulation of Vinyl Sulfoxonium Ylides with Quinones

S Deshwal, DS Davas, S Bhardwaj, J Vaitla - Organic Letters, 2024 - ACS Publications
Herein, we report the synthesis of 2 H-chromenes via catalyst-controlled highly
regioselective [3+ 3] annulation of vinyl sulfoxonium ylides with quinones. Under boron …

Hybrid Heterocycles: Ag(I)-Catalyzed C–C/C–N/C–O Coupled Cascade Dual Cyclization to Valuable Indolo-4H-indolones and Indolo-4H-chromenes

R Nandi, SK Ajarul, PK Mandal, AS Manna… - The Journal of …, 2024 - ACS Publications
Herein, we report a highly efficient Ag (I)-catalyzed indolyzation with Friedel–Crafts
alkylation through a cascade cyclization strategy for accessing valuable hybrid heterocycles …

Direct Z-Scheme gC3N5/Cu3TiO4 Heterojunction Enhanced Photocatalytic Performance of Chromene-3-Carbonitriles Synthesis under Visible Light Irradiation

M Arunachalapandi, T Chellapandi, G Madhumitha… - Catalysts, 2022 - mdpi.com
In order to make the synthesis of pharmaceutically active carbonitriles efficient,
environmentally friendly, and sustainable, the method is regularly examined. Here, we …

Recent Advances on Synthesis of 2H‐Chromenes, and Chromenes Fused Hetrocyclic Compounds

R Kumar Maurya, A Dey, V Kumara… - Asian Journal of …, 2024 - Wiley Online Library
Chromenes and 2H‐Chromenes are vital components of natural products, pharmaceuticals,
and agrochemicals that have captured the attention of researchers worldwide. These …

Novel Indole-Tethered Chromene Derivatives: Synthesis, Cytotoxic Properties, and Key Computational Insights

MS Malik, H Ather, SM Asif Ansari, A Siddiqua… - Pharmaceuticals, 2023 - mdpi.com
Indole-tethered chromene derivatives were synthesised in a one-pot multicomponent
reaction using N-alkyl-1 H-indole-3-carbaldehydes, 5, 5-dimethylcyclohexane-1, 3-dione …