Over the past decades, survival rates of childhood cancer have increased considerably from
5 to 30% in the early seventies to current rates exceeding 80%. This is due to the …

Background: Many childhood cancer survivors develop treatment-associated late effects
emerging years or even decades after the end of treatment. Evidence-based guidelines …

A long‐term follow‐up study was carried out to assess ototoxicity in children who had been
treated for a malignant tumour with “standard dose” cisplatin (60–; 100 mg/m2 per course) …

Aims Survival after cancer diagnosed during childhood or adolescence continues to improve
with new treatments and supportive therapies. Optimal long-term care requires that risks to …

Background Childhood cancer patients often remain uninformed regarding their potential
risk of gonadal damage. In our hospital we introduced a five step standard oncofertility care …

Patients given allogeneic hematopoietic stem cell transplantation (alloHSCT) present an
increased incidence of long-term toxicities that can be attributed to the preparative regimen …

Ototoxicity is a common side effect of platinum treatment and manifests as irreversible, high-
frequency sensorineural hearing loss. Genetic association studies have suggested a role for …

Progress in medicine has increased the survival time of children suffering from cancer;>
80% of patients survive for at least 5 years from the end of treatment. However, there are late …

Background Irreversible sensorineural hearing loss is a common side effect of platinum
treatment with the potential to significantly impair the neurocognitive, social and educational …

Irreversible sensorineural hearing loss is one of the most common side effects after cisplatin
treatment. Prevention and reversal of hearing loss caused by cisplatin are of great …