Frailty is a multiply determined, age-related state of increased risk for adverse health
outcomes. We review how the degree of frailty conditions the development of late-life …

Aging frailty is a complex geriatric syndrome that becomes more prevalent with advancing
age. It constitutes a major health problem due to frequent adverse outcomes. Frailty is …

Background The fraily index is a useful proxy measure of accelerated biological ageing and
in estimating all-cause and cause-specific mortality in older individuals in European and US …

Frailty is a common geriatric syndrome and strongly associated with disability, mortality and
hospitalization. Frailty is commonly measured using the frailty index (FI), based on the …

Biological age measurements (BAs) assess aging-related physiological change and predict
health risks among individuals of the same chronological age (CA). Multiple BAs have been …

Objectives Frailty is typically assessed in older populations. Identifying frailty in adults aged
under 60 years may also have value, if it supports the delivery of timely care. We sought to …

Background Sarcopenia and frailty are strongly associated with disease incidence and
mortality. However, there is limited evidence regarding their joint association with health …

Abstract Background/Objectives Frailty has been linked to increased risk of COVID‐19
mortality, but evidence is mainly limited to hospitalized older individuals. This study aimed to …

Identifying metabolic biomarkers of frailty, an age‐related state of physiological decline, is
important for understanding its metabolic underpinnings and developing preventive …

Background Frailty, sarcopenia, cachexia and malnutrition are clinical conditions that share
similar diagnostic criteria. This study aimed to investigate the clustering and mortality risk …