Giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) are two interrelated inflammatory diseases affecting patients above 50 years of age. Patients with GCA suffer …
CE McCarthy, JM White, NT Viola… - Frontiers in …, 2020 - frontiersin.org
The past two decades have brought impressive advancements in immune modulation, particularly with the advent of both cancer immunotherapy and biologic therapeutics for …
A Bouleau, V Lebon, C Truillet - Pharmacology & Therapeutics, 2021 - Elsevier
Despite the remarkable clinical successes of immune checkpoint inhibitors (ICIs) in various advanced cancers, response is still limited to a subset of patients that generally exhibit …
Z Yin, Y Zhang, X Wang - Biomarker Research, 2021 - Springer
B-cell non-Hodgkin lymphoma (B-NHL) is a group of heterogeneous disease which remains incurable despite developments of standard chemotherapy regimens and new therapeutic …
G Lv, Y Miao, Y Chen, C Lu, X Wang, M Xie, L Qiu… - Bioorganic …, 2021 - Elsevier
Programmed death ligand 1 (PD-L1) expression level is a reproducible biomarker for guiding stratification of patients to immunotherapy. However, the most widely used …
AM Wu, N Pandit-Taskar - Molecular Imaging and Biology, 2022 - Springer
Dramatic, but uneven, progress in the development of immunotherapies for cancer has created a need for better diagnostic technologies including innovative non-invasive imaging …
W Huang, G Huang, S An, J Liu - View, 2023 - Wiley Online Library
Pancreatic ductal adenocarcinoma (PDAC), a deadly cancer characterized by multiple molecular alterations, remains the most lethal cancer, with a 5‐year survival rate of about 3 …
C Rodriguez, S Delaney, SM Sarrett… - Journal of Nuclear …, 2022 - Soc Nuclear Med
Radiolabeled antibodies have become indispensable tools in nuclear medicine. However, the natural roles of antibodies within the immune system mean that they have several …
The concept of positron emission tomography (PET) based imaging was developed more than 40 years ago. It has been a widely adopted technique for detecting and staging …