Biologically active quinoline and quinazoline alkaloids part II

XF Shang, SL Morris‐Natschke… - Medicinal research …, 2018 - Wiley Online Library
To follow‐up on our prior Part I review, this Part II review summarizes and provides updated
literature on novel quinoline and quinazoline alkaloids isolated during the period of 2009 …

Therapeutic potential of quinazoline derivatives for Alzheimer's disease: A comprehensive review

Z Haghighijoo, L Zamani, F Moosavi… - European journal of …, 2022 - Elsevier
Quinazolines are considered as a promising class of bioactive heterocyclic compounds with
broad properties. Particularly, the quinazoline scaffold has an impressive role in the design …

Ultrasound for drug synthesis: a green approach

M Draye, G Chatel, R Duwald - Pharmaceuticals, 2020 - mdpi.com
This last century, the development of new medicinal molecules represents a real
breakthrough in terms of humans and animal life expectancy and quality of life. However …

Phytochemicals: potential lead molecules for MDR reversal

B Tinoush, I Shirdel, M Wink - Frontiers in Pharmacology, 2020 - frontiersin.org
Multidrug resistance (MDR) is one of the main impediments in the treatment of cancers.
MDR cancer cells are resistant to multiple anticancer drugs. One of the major mechanisms of …

Pyridyl Glycosyl Triazole/CuI-Mediated Domino/Tandem Synthesis of Quinazolinones

SK Singh, S Kumar, MS Yadav… - The Journal of Organic …, 2022 - ACS Publications
The glycosyl 1, 2, 3-triazoles are expediently accessible from readily available sugar-
derived glycosyl azide by utilizing modular CuAAC “Click Chemistry”, and the resulting …

Piperazine: a promising scaffold with analgesic and anti-inflammatory potential

A Jain, J Chaudhary, H Khaira, B Chopra… - Drug …, 2021 - thieme-connect.com
Piperazine, a nitrogen-containing heterocyclic has acquired an inimitable position in
medicinal chemistry because of its versatile structure, which has fascinated researchers to …

Recent advances in the synthesis of Quinazoline analogues as Anti-TB agents

A Dutta, D Sarma - Tuberculosis, 2020 - Elsevier
Quinazoline analogues are one of the important nitrogen containing heterocycles that have
significant bioactivity as well as found in a plethora of natural products. Tuberculosis is one …

Nanocarrier mediated co-delivery of phytochemicals and chemo-drugs: An emerging strategy to combat lung cancer in a systemic way

P Upadhyay, A Ghosh, V Sarangthem… - Phytochemistry Reviews, 2024 - Springer
Lung cancer is listed as one of the hotfooted malignancies on the basis of mortality and
morbidity. Thus, emergence of new targeting and immunotherapies is being recognized that …

Palladium(II) N^O Chelating Complexes Catalyzed One-Pot Approach for Synthesis of Quinazolin-4(3H)-ones via Acceptorless Dehydrogenative Coupling of Benzyl …

S Balaji, G Balamurugan, R Ramesh, D Semeril - Organometallics, 2021 - ACS Publications
A convenient protocol for the one-pot synthesis of quinazolin-4 (3 H)-ones using palladium
(II) complexes via dehydrogenative coupling of readily available benzyl alcohols and 2 …

Synthesis, X-ray Crystal Structure, and Antimicrobial Studies of New Quinazolin-4(3H)-one Derivatives Containing the 1,2,4-Triazolo[3,4-b][1,3,4]thiadiazole Moiety …

N Wu, Y Yang, G Tian, L An, S Liu, T Yan… - Journal of Agricultural …, 2023 - ACS Publications
A total of 35 new quinazolinone derivatives bearing the 1, 2, 4-triazolo [3, 4-b][1, 3, 4]
thiadiazole scaffold and the 4-piperidinyl linker were designed, prepared, and assessed for …