Monogenic diabetes refers to diabetes mellitus (DM) caused by a mutation in a single gene
and accounts for approximately 1%–5% of diabetes. Correct diagnosis is clinically critical for …

Maturity-onset diabetes of the young (MODY) is characterized by autosomal dominant
inheritance, onset before 25 years of age, absence of β-cell autoimmunity, and sustained …

Monogenic diabetes results from one or more defects in a single gene. The disease may be
inherited within families as a dominant, recessive or non-Mendelian trait or may present as a …

ISPAD Clinical Practice Consensus Guidelines 2022: The diagnosis and management of
monogenic diabetes in children and adolescents - PMC Back to Top Skip to main content NIH …

Gestational diabetes (GDM) is defined as a glucose intolerance resulting in hyperglycaemia
of variable severity with onset during pregnancy. This review aims to revisit the …

The hepatocyte nuclear factors (HNFs) namely HNF1α/β, FOXA1/2/3, HNF4α/γ and
ONECUT1/2 are expressed in a variety of tissues and organs, including the liver, pancreas …

Maturity-onset diabetes of the young (MODY) is an unusual form of diabetes with specific
features that distinguish it from type 1 and type 2 diabetes. There are 14 known subtypes of …

Executive summary This document updates the 1999 World Health Organization (WHO)
classification of diabetes. It prioritizes clinical care and guides health professionals in …

Maturity-onset diabetes of the young (MODY) is a group of monogenic disorders
characterized by autosomal dominantly inherited non-insulin dependent form of diabetes …

Glucokinase is a key regulatory enzyme in the pancreatic beta‐cell. It plays a crucial role in
the regulation of insulin secretion and has been termed the glucose sensor in pancreatic …