Chronic kidney disease (CKD) has a high prevalence in the general population and is associated with high mortality; a need therefore exists for better biomarkers for diagnosis …
The serum metabolome contains a plethora of biomarkers and causative agents of various diseases, some of which are endogenously produced and some that have been taken up …
Y Talmor-Barkan, N Bar, AA Shaul, N Shahaf… - Nature medicine, 2022 - nature.com
Complex diseases, such as coronary artery disease (CAD), are often multifactorial, caused by multiple underlying pathological mechanisms. Here, to study the multifactorial nature of …
The human gut is inhabited by a complex and metabolically active microbial ecosystem. While many studies focused on the effect of individual microbial taxa on human health, their …
T Long, M Hicks, HC Yu, WH Biggs, EF Kirkness… - Nature …, 2017 - nature.com
Genetic factors modifying the blood metabolome have been investigated through genome- wide association studies (GWAS) of common genetic variants and through exome …
After consumption of plant‐derived foods or beverages, dietary polyphenols such as quercetin are absorbed in the small intestine and metabolized by the body, or they are …
NMR measures a relatively small portion of the human metabolome, which roughly corresponds to all free small molecules present in concentrations≥ 1 μM. However, the …
MR Lewis, JTM Pearce, K Spagou, M Green… - Analytical …, 2016 - ACS Publications
To better understand the molecular mechanisms underpinning physiological variation in human populations, metabolic phenotyping approaches are increasingly being applied to …
KS Smirnov, TV Maier, A Walker, SS Heinzmann… - International Journal of …, 2016 - Elsevier
The review highlights the role of metabolomics in studying human gut microbial metabolism. Microbial communities in our gut exert a multitude of functions with huge impact on human …