[HTML][HTML] From genotypes to organisms: State-of-the-art and perspectives of a cornerstone in evolutionary dynamics

S Manrubia, JA Cuesta, J Aguirre, SE Ahnert… - Physics of Life …, 2021 - Elsevier
Understanding how genotypes map onto phenotypes, fitness, and eventually organisms is
arguably the next major missing piece in a fully predictive theory of evolution. We refer to this …

Natural variation in the consequences of gene overexpression and its implications for evolutionary trajectories

DE Robinson, M Place, J Hose, A Jochem, AP Gasch - Elife, 2021 - elifesciences.org
Copy number variation through gene or chromosome amplification provides a route for rapid
phenotypic variation and supports the long-term evolution of gene functions. Although the …

Ohnologs and SSD paralogs differ in genomic and expression features related to dosage constraints

Z Vance, A McLysaght - Genome Biology and Evolution, 2023 - academic.oup.com
Gene duplication is recognized as a critical process in genome evolution; however, many
questions about this process remain unanswered. Although gene duplicability has been …

Dosage balance acts as a time-dependent selective barrier to subfunctionalization

AE Wilson, DA Liberles - BMC Ecology and Evolution, 2023 - Springer
Background Gene duplication is an important process for genome expansion, sometimes
allowing for new gene functions to develop. Duplicate genes can be retained through …

Ancestry of the AUTS2 family–A novel group of polycomb-complex proteins involved in human neurological disease

RA Sellers, DL Robertson, M Tassabehji - Plos one, 2020 - journals.plos.org
Autism susceptibility candidate 2 (AUTS2) is a neurodevelopmental regulator associated
with an autosomal dominant intellectual disability syndrome, AUTS2 syndrome, and is …

Expectations of duplicate gene retention under the gene duplicability hypothesis

AE Wilson, DA Liberles - BMC Ecology and Evolution, 2023 - Springer
Background Gene duplication is an important process in evolution. What causes some
genes to be retained after duplication and others to be lost is a process not well understood …

Evidence from Drosophila supports higher duplicability of faster evolving genes

Z Vance, L Niezabitowski, LD Hurst… - Genome biology and …, 2022 - academic.oup.com
The faster rate of evolution of duplicated genes relative to singletons has been well
documented in multiple lineages. This observation has generally been attributed to a …

SELECTIVE FORCES SHAPING DUPLICATE GENE EVOLUTION: INSIGHTS FROM STOCHASTIC MODELING AND PATTERNS OF RETENTION

AE Wilson - 2024 - scholarshare.temple.edu
The variation of genome content and structure across the tree of life is astounding and can
provide clues to understand the process of evolution. Overall, this helps us understand the …

Enrichment of intrinsically disordered residues in ohnologs facilitates abiotic stress resilience in Brassica rapa

S Das Laha, D Das, T Ghosh, S Podder - Journal of Plant Research, 2023 - Springer
Arabidopsis thaliana and Brassica rapa are in the same evolutionary lineage, although the
latter experienced an additional whole genome triplication event. Therefore, it would be …

阿拉伯芥轉錄因子ICE1 之重組蛋白表現及結構分析

YA Lin - 臺灣大學生化科技學系學位論文, 2019 - airitilibrary.com
Inducer of CBF Expression 1 (ICE1) is a MYC-like basic helix-loop-helix (bHLH) transcription
factor in Arabidopsis thaliana. ICE1 interacts with or subjects to be post-translational …