DNA is traditionally known as a central genetic biomolecule in living systems. From an
alternative perspective, DNA is a versatile molecular building-block for the construction of …

Developing powerful, simple and low-cost DNA amplification techniques is of great
significance to bioanalysis and biomedical research. Thus far, many signal amplification …

DNA hydrogels hold great potential for biological and biomedical applications owing to their
programmable nature and macroscopic sizes. However, most previous studies involve …

Human telomerase RNA (hTR), an important biomarker for cancer diagnosis, is the template
for the synthesis of telomeric DNA repeats and is found to be 7-fold overexpressed in tumor …

Herein a versatile photoelectrochemical (PEC) bioanalysis platform for sensitive and specific
screening of low-abundance antibiotics (kanamycin, Kana, used in this case) was …

To pursue the sensitive and efficient detection of informative biomolecules for bioanalysis
and disease diagnosis, a series of signal amplification techniques have been put forward …

The detection of tumor-associated biomarkers contributes to personalized precision medical
treatment of cancer patients in early stage. Combined with nucleic acid amplification …

In the last decade, nanotechnology has been extensively introduced for biomedical
applications, including bio-detection, drug delivery and diagnostic imaging, particularly in …

We present a nonlinear hybridization chain reaction (HCR) system in which a trigger DNA
initiates self-sustained assembly of quenched double-stranded substrates into fluorescent …

Hybridization chain reaction (HCR) can be divided into two categories: linear HCR and
nonlinear HCR. In traditional linear HCR, the relatively slow kinetics and less sufficient …