This paper reviews the methods, benefits and challenges associated with the adoption and
translation of computational fluid dynamics (CFD) modelling within cardiovascular medicine …

Importance Computed tomography–derived fractional flow reserve (FFR-CT) is a novel,
noninvasive test for myocardial ischemia. Clinicians using FFR-CT must be able to interpret …

Providing therapies tailored to each patient is the vision of precision medicine, enabled by
the increasing ability to capture extensive data about individual patients. In this position …

Objectives We aimed to develop a novel wire‐and adenosine‐free microcirculatory resistive
index from functional angiography (angio‐IMR) to estimate coronary microcirculatory …

Objectives: The authors sought to evaluate the influence of coronary microcirculatory
dysfunction (CMD) on the diagnostic performance of the quantitative flow ratio (QFR) …

Background—Fractional flow reserve (FFR), an index of the hemodynamic severity of
coronary stenoses, is derived from invasive measurements and requires a pressure …

Hemodynamics interacts with the cellular components of human vessels, influencing
function and healthy status. Locally acting hemodynamic forces have been associated—by a …

Fractional flow reserve (FFR)-guided percutaneous intervention is superior to standard
assessment but remains underused. The authors have developed a novel “pseudotransient” …

Despite continuous progress in X-ray angiography systems, X-ray coronary angiography is
fundamentally limited by its 2D representation of moving coronary arterial trees, which can …

Coronary outlet resistance, influenced by quantification and distribution of total hyperemic
coronary blood flow, is critical for accurately estimating the computation of fractional flow …