Validation of biomarkers of aging

M Moqri, C Herzog, JR Poganik, K Ying, JN Justice… - Nature medicine, 2024 - nature.com
The search for biomarkers that quantify biological aging (particularly 'omic'-based
biomarkers) has intensified in recent years. Such biomarkers could predict aging-related …

Organ-specific biological clocks: Ageotyping for personalized anti-aging medicine

F Prattichizzo, C Frigé, V Pellegrini, L Scisciola… - Ageing Research …, 2024 - Elsevier
Aging is a complex multidimensional, progressive remodeling process affecting multiple
organ systems. While many studies have focused on studying aging across multiple organs …

Evaluating facial dermis aging in healthy Caucasian females with LC-OCT and deep learning

A Assi, S Fischman, C Lopez, M Pedrazzani… - Scientific Reports, 2024 - nature.com
Recent advancements in high-resolution imaging have significantly improved our
understanding of microstructural changes in the skin and their relationship to the aging …

The association between sleep quality and accelerated epigenetic aging with metabolic syndrome in Korean adults

HS Lee, B Kim, T Park - Clinical Epigenetics, 2024 - Springer
Background Healthy sleep is vital for maintaining optimal mental and physical health.
Accumulating evidence suggests that sleep loss and disturbances play a significant role in …

[HTML][HTML] Multiomics of Aging and Aging-Related Diseases

OI Kiseleva, VA Arzumanian, YA Ikhalaynen… - International Journal of …, 2024 - mdpi.com
Despite their astonishing biological diversity, surprisingly few shared traits connect all or
nearly all living organisms. Aging, ie, the progressive and irreversible decline in the function …

Ratio of Red Blood Cell Distribution Width to Albumin Level and Risk of Mortality

M Hao, S Jiang, J Tang, X Li, S Wang, Y Li… - JAMA Network …, 2024 - jamanetwork.com
Importance The ratio of red blood cell distribution width (RDW) to albumin concentration
(RAR) has emerged as a reliable prognostic marker for mortality in patients with various …

[PDF][PDF] Validation of biomarkers of aging

Biomarkers of Aging Consortium - Nature Medicine, 2024 - research.ed.ac.uk
Brain Development Network, Canadian Institute for Advanced Research and SocioMed
Research 87 Nucleus, Universidad Mayor, Santiago, Chile. DB is an inventor of …

MANOCCA: a robust and computationally efficient test of covariance in high-dimension multivariate omics data

C Boetto, A Frouin, L Henches… - Briefings in …, 2024 - academic.oup.com
Multivariate analysis is becoming central in studies investigating high-throughput molecular
data, yet, some important features of these data are seldom explored. Here, we present …

[HTML][HTML] Identifying potential predictors of surgical site infection risk following cardiac surgery: a scoping review

KV Charlwood, J Jackson, R Vaja, LJ Rogers… - Journal of Hospital …, 2024 - Elsevier
Objectives This scoping review was undertaken to identify risk predictions models and
preoperative predictors of surgical site infection (SSI) in adult cardiac surgery. A particular …

An expert consensus statement on biomarkers of ageing for use in intervention studies

G Perri, C French, C Agostinis-Sobrinho… - The Journals of …, 2024 - academic.oup.com
Biomarkers of ageing serve as important outcome measures in longevity-promoting
interventions. However, there is limited consensus on which specific biomarkers are most …