Progress in understanding of the mechanisms underlying chronic inflammatory skin
disorders, such as atopic dermatitis and psoriasis vulgaris, has led to new treatment options …

Objective To provide an overview of filaggrin biology and the role of filaggrin variants in
atopic dermatitis (AD) and allergic disease. Data Sources We performed a PubMed literature …

Atopic dermatitis (AD) is a highly pruritic, chronic inflammatory skin disease. The diagnosis
is made using evaluated clinical criteria. Disease activity and burden are best measured …

As an interface with the environment, the skin is a complex ecosystem colonized by many
microorganisms that coexist in an established balance. The cutaneous microbiome inhibits …

The skin is a complex layer system and the most important barrier between the environment
and the organism. In this review, we describe some widespread skin problems, with a focus …

Spaceflight can change metabolic, immunological, and biological homeostasis and cause
skin rashes and irritation, yet the molecular basis remains unclear. To investigate the impact …

Author summary Our skin is our first line of defense against environmental and pathogenic
challenges. It is densely populated by a flora of bacteria, fungi, and viruses that normally …

The human skin harbors a wide variety of microbes that, together with their genetic
information and host interactions, form the human skin microbiome. The role of the human …

Staphylococcus aureus is a very common Gram-positive bacterium, and S. aureus infections
play an extremely important role in a variety of diseases. This paper describes the types of …

Antimicrobial resistance constitutes one of the major challenges facing humanity in the
Twenty-First century. The spread of resistant pathogens has been such that the possibility of …