When Will Real-World Data Fulfill Its Promise to Provide Timely Insights in Oncology?
ML Berger, PA Ganz, KH Zou… - JCO Clinical Cancer …, 2024 - ascopubs.org
Randomized trials provide high-quality, internally consistent data on selected clinical
questions, but lack generalizability for the aging population who are most often diagnosed …
questions, but lack generalizability for the aging population who are most often diagnosed …
[HTML][HTML] Design differences and variation in results between randomised trials and non-randomised emulations: meta-analysis of RCT-DUPLICATE data
Objective To explore how design emulation and population differences relate to variation in
results between randomised controlled trials (RCT) and non-randomised real world …
results between randomised controlled trials (RCT) and non-randomised real world …
[HTML][HTML] Leveraging real-world data to assess treatment sequences in health economic evaluations: a study protocol for emulating target trials using the English …
JYA Chang, JB Chilcott… - HEDS Discussion …, 2024 - eprints.whiterose.ac.uk
Background Considering the sequence of treatments is vital for optimising healthcare
resource allocation, especially in cancer care, where sequence changes can affect patients' …
resource allocation, especially in cancer care, where sequence changes can affect patients' …
Enhancing External Control Arm Analyses through Data Calibration and Hybrid Designs
S Schneeweiss - Clinical Pharmacology & Therapeutics - Wiley Online Library
Almost all external control arm analyses to contextualize findings of a single arm trial
struggle with two key issues: the lack of baseline randomization, and equally important, the …
struggle with two key issues: the lack of baseline randomization, and equally important, the …