[HTML][HTML] Telomere-specific regulation of TERRA and its impact on telomere stability

J Rivosecchi, K Jurikova, E Cusanelli - Seminars in Cell & Developmental …, 2024 - Elsevier
TERRA is a class of telomeric repeat-containing RNAs that are expressed from telomeres in
multiple organisms. TERRA transcripts play key roles in telomere maintenance and their …

[HTML][HTML] G-quadruplexes in Human telomere: structures, properties, and applications

Y Xu, M Komiyama - Molecules, 2023 - mdpi.com
G-quadruplexes, intricate four-stranded structures composed of G-tetrads formed by four
guanine bases, are prevalent in both DNA and RNA. Notably, these structures play pivotal …

Dominant and genome-wide formation of DNA: RNA hybrid G-quadruplexes in living yeast cells

C Ren, R Duan, J Wang, Y Hao, Z Tan - Proceedings of the National …, 2024 - pnas.org
Guanine-rich DNA forms G-quadruplexes (G4s) that play a critical role in essential cellular
processes. Previous studies have mostly focused on intramolecular G4s composed of four …

Unearthing a novel function of SRSF1 in binding and unfolding of RNA G-quadruplexes

NIU De Silva, N Lehman, T Fargason… - Nucleic Acids …, 2024 - academic.oup.com
SRSF1 governs splicing of over 1500 mRNA transcripts. SRSF1 contains two RNA-
recognition motifs (RRMs) and a C-terminal Arg/Ser-rich region (RS). It has been thought …

Slow G-Quadruplex Conformation Rearrangement and Accessibility Change Induced by Potassium in Human Telomeric Single-Stranded DNA

AN Lacen, A Symasek, A Gunter… - The Journal of Physical …, 2024 - ACS Publications
The guanine-rich telomeric repeats can form G-quadruplexes (G4s) that alter the
accessibility of the single-stranded telomeric overhang. In this study, we investigated the …

Genome-Wide Formation of DNA: RNA Hybrid G-Quadruplexes in Live Yeast Cells

C Ren, R Duan, Y Hao, Z Tan - bioRxiv, 2023 - biorxiv.org
Four-stranded G-quadruplex (G4) structures formed by guanine-rich nucleic acids play a
role in many essential physiological processes. To date, studies have focused almost …