Quorum-sensing systems as targets for antivirulence therapy

T Defoirdt - Trends in microbiology, 2018 - cell.com
The development of novel therapies to control diseases caused by antibiotic-resistant
pathogens is one of the major challenges we are currently facing. Many important plant …

Innovative microbial disease biocontrol strategies mediated by quorum quenching and their multifaceted applications: A review

X Zhu, WJ Chen, K Bhatt, Z Zhou, Y Huang… - Frontiers in Plant …, 2023 - frontiersin.org
With the increasing resistance exhibited by undesirable bacteria to traditional antibiotics, the
need to discover alternative (or, at least, supplementary) treatments to combat chemically …

Versatile polymer-based strategies for antibacterial drug delivery systems and antibacterial coatings

K You, B Gao, M Wang, X Wang, KC Okoro… - Journal of Materials …, 2022 - pubs.rsc.org
Human health damage and economic losses due to bacterial infections are very serious
issues worldwide. Excessive use of antibiotics has caused an increase in bacterial …

Surface-attached molecules control Staphylococcus aureus quorum sensing and biofilm development

MK Kim, A Zhao, A Wang, ZZ Brown, TW Muir… - Nature …, 2017 - nature.com
Bacteria use a process called quorum sensing to communicate and orchestrate collective
behaviours, including virulence factor secretion and biofilm formation. Quorum sensing …

Nanocarriers from GRAS zein proteins to encapsulate hydrophobic actives

NT Weissmueller, HD Lu, A Hurley… - …, 2016 - ACS Publications
One factor limiting the expansion of nanomedicines has been the high cost of the materials
and processes required for their production. We present a continuous, scalable, low cost …

Flash technology-based self-assembly in nanoformulation: Fabrication to biomedical applications

H Hu, C Yang, M Li, D Shao, HQ Mao, KW Leong - Materials Today, 2021 - Elsevier
Advances in nanoformulation have driven progress in biomedicine by producing nanoscale
tools for biosensing, imaging, and drug delivery. Flash-based technology, the combination of …

Slippery liquid-infused porous surfaces that prevent bacterial surface fouling and inhibit virulence phenotypes in surrounding planktonic cells

MJ Kratochvil, MA Welsh, U Manna, BJ Ortiz… - ACS infectious …, 2016 - ACS Publications
Surfaces that can both prevent bacterial biofouling and inhibit the expression of virulence
phenotypes in surrounding planktonic bacteria are of interest in a broad range of contexts …

Nanomaterials and coatings for managing antibiotic-resistant biofilms

G Ferreres, K Ivanova, I Ivanov, T Tzanov - Antibiotics, 2023 - mdpi.com
Biofilms are a global health concern responsible for 65 to 80% of the total number of acute
and persistent nosocomial infections, which lead to prolonged hospitalization and a huge …

Attenuation of quorum sensing system and virulence in Vibrio cholerae by phytomolecules

S Saha, S Aggarwal, DV Singh - Frontiers in Microbiology, 2023 - frontiersin.org
The Vibrio cholerae, a gram-negative bacterium, is the causative agent of cholera. Quorum
sensing is a cell-to-cell communication that leads to gene expression, accumulation of …

Light-activable on-demand release of nano-antibiotic platforms for precise synergy of thermochemotherapy on periodontitis

L Zhang, Y Wang, C Wang, M He, J Wan… - … applied materials & …, 2019 - ACS Publications
The overprescription and improper use of antibiotics have contributed to the evolution of
bacterial resistance, making it urgent to develop alternative therapies and agents with better …