Stroke is the leading cause of disability and thesecond leading cause of death worldwide.
With the global population aged 65 and over growing faster than all other age groups, the …

Acute ischemic stroke is a common cause of morbidity and mortality worldwide.
Thrombolysis with recombinant tissue plasminogen activator and endovascular …

Background Remote ischaemic conditioning with transient ischaemia and reperfusion
applied to the arm has been shown to reduce myocardial infarct size in patients with ST …

Importance Preclinical and clinical studies have suggested a neuroprotective effect of
remote ischemic conditioning (RIC), which involves repeated occlusion/release cycles on …

Background Remote ischemic preconditioning (RIPC) is reported to reduce biomarkers of
ischemic and reperfusion injury in patients undergoing cardiac surgery, but uncertainty …

The treatment of acute ischemic stroke has undergone dramatic changes recently
subsequent to the demonstrated efficacy of intra-arterial (IA) device-based therapy in …

Background and Purpose—Treatment options for patients with acute ischemic stroke
depend on the volume of salvageable tissue. This volume assessment is currently based on …

Investigators acknowledge the limitations of rodent or non-human primate stroke models,
hundreds of putative neuroprotectants have been evaluated in preclinical models, but not …

Intrapartum-related events are the third leading cause of childhood mortality worldwide and
result in one million neurodisabled survivors each year. Infants exposed to a perinatal insult …

Background Intracranial atherosclerotic stenosis (ICAS) is one of the most common causes
of stroke worldwide, and it is associated with a high risk of recurrent stroke with currently …