Chronic pain is associated with abnormal excitability of the somatosensory system and
remains poorly treated in the clinic. Potassium (K+) channels are crucial determinants of …

Recent biochemical observations have helped redefine antigenic components within the
voltage-gated potassium channel (VGKC) complex. The related autoantibodies may be now …

The American Society for Apheresis (ASFA) JCA Special Issue Writing Committee is
charged with reviewing, updating and categorizating indications for therapeutic apheresis …

Antibodies that immunoprecipitate 125I-α-dendrotoxin-labelled voltage-gated potassium
channels extracted from mammalian brain tissue have been identified in patients with …

Clinicians use many terms including undulating myokymia, neuromyotonia, Isaacs'
syndrome and Cramp–Fasciculation Syndrome to describe the motor manifestations of …

Morvan's 'fibrillary chorea'or Morvan's syndrome is characterized by neuromyotonia (NMT),
pain, hyperhydrosis, weight loss, severe insomnia and hallucinations. We describe a man …

Acquired neuromyotonia is characterized by hyperexcitability of motor nerves leading to
muscle twitching, cramps, and weakness. The symptoms may improve following plasma …

At least 13 different disease entities affecting the central nervous system, peripheral nervous
system and connective tissue of the skin or kidneys are associated with immunoglobulin G4 …

Antibody‐mediated autoimmunity underlies a diverse range of disorders, particularly in the
nervous system where the extracellular domains of ion channels and receptors are …

Neuromyotonia is a syndrome of spontaneously occurring muscle activity of peripheral
nerve origin, which can be triggered by voluntary or induced muscle contraction. It is one …