Accurate, robust and reproducible delineation of tumour in Positron Emission Tomography
(PET) is essential for diagnosis, treatment planning and response assessment. Since …

Abstract Total-Body (TB) PET/computed tomography (CT) provides a substantial gain in the
physical sensitivity of PET, leading to vastly improved image quality or can enable imaging …

Musculoskeletal disorders (MSDs) are broadly defined as diseases or injuries of the joints,
bones, muscles, nerves, tendons, ligaments, supporting soft tissues, cartilage, and spinal …

Total-body PET (TB-PET) imaging is an evolving technology addressing the limitations of
conventional PET imaging. With a fundamentally novel approach for its geometric coverage …

It is known that metabolic shifts and tissue remodelling precede the development of visible
inflammation and structural organ damage in inflammatory rheumatic diseases such as the …

The bone-seeking properties of 18F-sodium fluoride (NaF) were first described in 1962 by
Blau and colleagues, 1 who used this positron-emitting radiotracer in skeletal scintigraphy …

Background The present study aimed to investigate the clinical implication of F-18 sodium
fluoride (NaF) positron emission tomography/computed tomography (PET/CT) for assessing …

Bone remodeling is an important physiologic process for replacing old bone with newer and
healthier bone. This remodeling process requires the constant activity of osteoclasts, which …

Rheumatoid Arthritis (RA) is a systemic inflammatory disorder that commonly presents with
polyarthritis but can have multisystemic involvement and complications, leading to increased …

Objectives The aim of this study was to quantify subchondral bone remodeling in the elbows,
hands, knees, and feet using volumetric and metabolic parameters derived from 18 F …