Epithelial-mesenchymal transition (EMT) is a cellular biological process involved in
migration of primary cancer cells to secondary sites facilitating metastasis. Besides, EMT …

Hypoxia has been shown to increase the aggressiveness and severity of tumor progression.
Along with chronic and acute hypoxic regions, solid tumors contain regions of cycling …

Simple Summary Hypoxia is defined as the inadequate supply of oxygen in tissues. Regions
of acute and chronic hypoxia are a universal feature of the tumor microenvironment and a …

Y-box binding proteins (YB proteins) are DNA/RNA-binding proteins belonging to a large
family of proteins with the cold shock domain. Functionally, these proteins are known to be …

Most conventional incubators used in cell culture do not regulate O2 levels, making the
headspace O2 concentration~ 18%. In contrast, most human tissues are exposed to 2–6 …

Oxygen is essential for viability in mammalian organisms. However, cells are often exposed
to changes in oxygen availability, due to either increased demand or reduced oxygen …

Hypoxia-inducible factor 1 can sufficiently control the progress of neurological symptoms
after ischemic stroke owing to their actions associated with its downstream genes. In this …

Hypoxia has a significant impact on many physiological and pathological processes. Over
the recent years, its role in modulation of epigenetic remodelling has also become clearer. In …

Protein translation is a tightly regulated cellular process that is essential for gene expression
and protein synthesis. The deregulation of this process is increasingly recognized as a …

Sepsis is a highly heterogeneous syndrome that is caused by an imbalanced host response
to infection. Despite huge investments, sepsis remains a contemporary threat with significant …