Schlafen (SLFN) genes belong to a vertebrate gene family encoding proteins with high
sequence homology. However, each SLFN is functionally divergent and differentially …

The Schlafen (SLFN) family of proteins includes several mouse and human members. There
is emerging evidence that members of this family of proteins are involved in important …

We report full-length draft de novo genome assemblies for 16 widely used inbred mouse
strains and find extensive strain-specific haplotype variation. We identify and characterize …

Transient populations of cis-and trans-acting small RNAs have recently emerged as key
regulators of extensive epigenetic changes taking place during periconception, which …

Transposable elements are genomic parasites that expand within and spread between
genomes. PIWI proteins control transposon activity, notably in the germline,. These proteins …

Genes of the Schlafen family, first discovered in mouse, are expressed in hematopoietic
cells and are involved in immune processes. Previous results showed that they are …

IFNα exerts potent inhibitory activities against malignant melanoma cells in vitro and in vivo,
but the mechanisms by which it generates its antitumor effects remain unknown. We …

Schlafen (SLFN/Slfn) family members have been investigated for their involvement in
fundamental cellular processes including growth regulation, differentiation and control of …

The oocyte is a unique and highly specialized cell responsible for creating, activating, and
controlling the embryonic genome, as well as supporting basic processes such as cellular …

We provide evidence that human SLFN5, an interferon (IFN)-inducible member of the
Schlafen (SLFN) family of proteins, exhibits key roles in controlling motility and invasiveness …