Native mass spectrometry (nMS) is evolving into a workhorse for structural biology. The
plethora of online and offline preparation, separation, and purification methods as well as …

Several approaches to ion activation in tandem mass spectrometry have been developed in
recent years for use in ion trapping instruments that allow for conditions to be reached …

Tandem mass spectrometry (MS/MS) employs two stages of mass analysis in order to
examine selectively the fragmentation of particular ions in a mixture of ions. The various …

This review presents a brief historical introduction to the development of tandem mass
spectrometry and its principal applications. It is placed in the context of the general …

The internal energy of an ion has a very large effect on the appearance of the mass
spectrum. The first part of this paper gives the theoretical background:(i) dependence of the …

The utility of surface‐induced dissociation (SID) to probe the structure, energetics and
fragmentation mechanisms of protonated peptides is discussed and demonstrated. High …

METHODS Herein we describe alternative dissociation methods commonly employed within
mass spectrometry with an emphasis on the outcomes of probing native protein complexes …

Mass spectrometry (MS), a century-old analytical technique, is now emerging as a
preparative method. Electrospray deposition (ESD) of charged droplets generated by …

A method of preparing modified surfaces, referred to as soft-landing, is described in which
intact polyatomic ions are deposited from the gas phase into a monolayer fluorocarbon …

An overview of gaseous ion/surface collisions is presented, with special emphasis on the
behavior of polyatomic projectile ions at hyperthermal collision energies (1–100 eV) and the …