Estrogen, stress, and depression: cognitive and biological interactions
KM Albert, PA Newhouse - Annual review of clinical psychology, 2019 - annualreviews.org
This article reviews the interactions of estrogen changes and psychosocial stress in
contributing to vulnerability to major depressive disorder (MDD) in women. Estrogen …
contributing to vulnerability to major depressive disorder (MDD) in women. Estrogen …
Depression, antidepressants, and neurogenesis: a critical reappraisal
ND Hanson, MJ Owens, CB Nemeroff - Neuropsychopharmacology, 2011 - nature.com
The neurogenesis hypothesis of depression posits (1) that neurogenesis in the subgranular
zone of the dentate gyrus is regulated negatively by stressful experiences and positively by …
zone of the dentate gyrus is regulated negatively by stressful experiences and positively by …
Reduced olfactory bulb volume and olfactory sensitivity in patients with acute major depression
The purpose of this study was to assess olfactory function and olfactory bulb volume in
patients with acute major depression in comparison to a normal population. Twenty-one …
patients with acute major depression in comparison to a normal population. Twenty-one …
Adult neurogenesis and mental illness
TJ Schoenfeld, HA Cameron - Neuropsychopharmacology, 2015 - nature.com
Several lines of evidence suggest that adult neurogenesis, the production of new neurons in
adulthood, may play a role in psychiatric disorders, including depression, anxiety, and …
adulthood, may play a role in psychiatric disorders, including depression, anxiety, and …
Serotonin4 (5-HT4) receptor agonists are putative antidepressants with a rapid onset of action
G Lucas, VV Rymar, J Du, O Mnie-Filali, C Bisgaard… - Neuron, 2007 - cell.com
Current antidepressants are clinically effective only after several weeks of administration.
Here, we show that serotonin 4 (5-HT 4) agonists reduce immobility in the forced swimming …
Here, we show that serotonin 4 (5-HT 4) agonists reduce immobility in the forced swimming …
Effects of steroid hormones on neurogenesis in the hippocampus of the adult female rodent during the estrous cycle, pregnancy, lactation and aging
Adult neurogenesis exists in most mammalian species, including humans, in two main
areas: the subventricular zone (new cells migrate to the olfactory bulbs) and the dentate …
areas: the subventricular zone (new cells migrate to the olfactory bulbs) and the dentate …
Chronic corticosterone during pregnancy and postpartum affects maternal care, cell proliferation and depressive-like behavior in the dam
S Brummelte, LAM Galea - Hormones and behavior, 2010 - Elsevier
Stress during pregnancy and the postpartum can influence the well-being of both the mother
and her offspring. Prolonged elevated levels of glucocorticoids are associated with …
and her offspring. Prolonged elevated levels of glucocorticoids are associated with …
Adult neurogenesis in Parkinson's disease
Abstract Parkinson's disease (PD), the second most common neurodegenerative disorder,
affects 1–2% of humans aged 60 years and older. The diagnosis of PD is based on motor …
affects 1–2% of humans aged 60 years and older. The diagnosis of PD is based on motor …
The olfactory bulbectomized rat as a model of depression: the hippocampal pathway
In rodents, the removal of the olfactory bulbs (OBs), ie olfactory bulbectomy (OBX), results in
numerous alterations in neurotransmitter, endocrine and immune systems, as well as …
numerous alterations in neurotransmitter, endocrine and immune systems, as well as …
Influence of sex and stress exposure across the lifespan on endophenotypes of depression: focus on behavior, glucocorticoids, and hippocampus
AR Gobinath, R Mahmoud, LAM Galea - Frontiers in neuroscience, 2015 - frontiersin.org
Sex differences exist in vulnerability, symptoms, and treatment of many neuropsychiatric
disorders. In this review, we discuss both preclinical and clinical research that investigates …
disorders. In this review, we discuss both preclinical and clinical research that investigates …