Dexmedetomidine use in general anaesthesia

A Arcangeli, C D'alo, R Gaspari - Current drug targets, 2009 - ingentaconnect.com
Dexmedetomidine is a potent and highly selective α2-adrenoreceptor agonist currently
utilized for continuous infusion for sedation/analgesia in the intensive care unit (ICU) …

Perioperative dexmedetomidine for acute pain after abdominal surgery in adults

LJ Lundorf, HK Nedergaard… - Cochrane Database of …, 2016 - cochranelibrary.com
Background Acute postoperative pain is still an issue in patients undergoing abdominal
surgery. Postoperative pain and side effects of analgesic treatment, in particular those of …

[PDF][PDF] Intravenous dexmedetomidine, but not midazolam, prolongs bupivacaine spinal anesthesia

FN Kaya, B Yavascaoglu, G Turker… - Canadian Journal …, 2010 - acikerisim.uludag.edu.tr
Conclusion Intravenous dexmedetomidine, but not midazolam, prolonged spinal
bupivacaine sensory blockade. It also provided sedation and additional analgesia. Résumé …

Premedication for anxiety in adult day surgery

KJ Walker, AF Smith - Cochrane database of systematic …, 2009 - cochranelibrary.com
Background Since the early 1980s, it has become more and more common to carry out
surgical procedures on a day case basis. Many patients are anxious before surgery yet there …

Effect of dexmedetomidine on hemodynamic responses to tracheal intubation: A meta-analysis with meta-regression and trial sequential analysis.

A De Cassai, A Boscolo, F Geraldini… - Journal of clinical …, 2021 - Elsevier
Study objective An uncontrolled adrenergic response during tracheal intubation may lead to
life-threatening complications. Dexmedetomidine binds to α2-receptors and may attenuate …

Induced hypotension for functional endoscopic sinus surgery: A comparative study of dexmedetomidine versus esmolol

T Shams, NS El Bahnasawe… - Saudi journal of …, 2013 - journals.lww.com
Objective: A comparative study to evaluate the efficacy of dexmedetomidine as a
hypotensive agent in comparison to esmolol in Functional Endoscopic Sinus Surgery …

Efficacy of dexmedetomidine in suppressing cardiovascular and hormonal responses to general anaesthesia for caesarean delivery: a dose–response study

MR El-Tahan, HA Mowafi, IH Al Sheikh… - International journal of …, 2012 - Elsevier
BACKGROUND: Preoperative dexmedetomidine administration blunts haemodynamic and
hormonal responses to tracheal intubation and reduces anaesthetic requirements. We …

Alpha‐2 adrenergic agonists for the prevention of cardiac complications among adults undergoing surgery

D Duncan, A Sankar, WS Beattie… - Cochrane Database …, 2018 - cochranelibrary.com
Background The surgical stress response plays an important role on the pathogenesis of
perioperative cardiac complications. Alpha‐2 adrenergic agonists attenuate this response …

Nitroglycerine, esmolol and dexmedetomidine for induced hypotension during functional endoscopic sinus surgery: A comparative evaluation

SJS Bajwa, J Kaur, A Kulshrestha… - Journal of …, 2016 - journals.lww.com
Conclusion: Dexmedetomidine and esmolol provided better hemodynamic stability and
operative field visibility compared to nitroglycerin during FESS. Dexmedetomidine provides …

[HTML][HTML] Effect of preoperative dexmedetomidine nebulization on the hemodynamic response to laryngoscopy and intubation: a randomized control trial

S Misra, BK Behera, JK Mitra… - Korean journal of …, 2021 - synapse.koreamed.org
Background Dexmedetomidine, an alpha-2 agonist, has been used for attenuation of
hemodynamic response to laryngoscopy but not through the nebulized route. We evaluated …