Catalyst-Free Cascade Annulation of Enaminones and Aryl Diazonium Tetrafluoroboronates for Cinnoline Synthesis and the Anti-Inflammatory Activity Study

S Tian, Y Liu, C Wan, JP Wan… - The Journal of Organic …, 2023 - ACS Publications
A simple and concise method for the synthesis of cinnolines has been developed by the
reactions of readily available enaminones and aryl diazonium tetrafluoroboronates. The …

The Precious Potential of the Sacred Tree Chamaecyparis obtusa (Siebold & Zucc.) Endl. as a Source of Secondary Metabolites with Broad Biological Applications

KM Górski, T Kowalczyk, L Picot, P Rijo… - International Journal of …, 2024 - mdpi.com
Chamaecyparis obtusa (Siebold & Zucc.) Endl., which belongs to the Cupressaceae family,
occurs naturally in North America and Asia, especially in Korea, Taiwan and Japan, where it …

Metal-free three-component assemblies of anilines, α-keto acids and alkyl lactates for quinoline synthesis and their anti-inflammatory activity

L Huang, L Yang, JP Wan, L Zhou, Y Liu… - Organic & Biomolecular …, 2022 - pubs.rsc.org
A new and metal-free three-component method for the synthesis of 2, 4-disubstituted
quinolines via the reactions of anilines, α-keto acids and alkyl lactates is reported. The …

[HTML][HTML] Pharmacological anti-tumor effects of natural Chamaecyparis obtusa (siebold & zucc.) endl. Leaf extracts on breast cancer

YJ Kwon, EB Seo, SK Kim, HS Lee, H Lee… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Chamaecyparis obtusa (C. obtusa, cypress species) is a
plant that grows mainly in the temperate Northern Hemisphere and has long been used as a …

Anti-Inflammatory Effects of Chamaecyparis obtusa (Siebold & Zucc.) Endl. Leaf Extract Fermented by Ganoderma applanatum Mycelia

CH Kim, YJ Kwon, YA Jang - Pharmaceutics, 2024 - mdpi.com
Corticosteroids are commonly used anti-inflammatory agents. However, their prolonged use
can lead to side effects. Therefore, the development of natural compounds with minimal side …

Anti-Inflammatory Effect of Chamaecyparis obtusa (Siebold & Zucc.) Endl. Leaf Essential Oil

SH Kim, YA Jang, YJ Kwon - Molecules, 2024 - mdpi.com
Chamaecyparis obtusa (Siebold & Zucc.) Endl.(C. obtusa) belongs to the Cupressaceae
family and is native to East Asian regions. Essential oils extracted from the leaves, bark …

[HTML][HTML] Siweixizangmaoru Decoction Ameliorated Type II Collagen-Induced Arthritis in Rats via Regulating JAK2–STAT3 and NF-κB Signaling Pathway

Y Niu, Q Feng, M Cui, C Fan, T Wang… - Biological and …, 2024 - jstage.jst.go.jp
Siweixizangmaoru decoction (SXD) is widely used as an anti-rheumatoid arthritis (RA) in
Tibet, however, the specific anti-inflammatory mechanism of SXD is still unclear. This …

Unraveling the Dual Anti‐Inflammatory and Antioxidant Mechanisms of Acteoside: Computational Insights and Experimental Validation

E Muhtar, G Ylham, A Tiemuer… - Chemistry & …, 2024 - Wiley Online Library
Acteoside (ACT) is one of the primary bioactive ingredients in Cistanche tubulosa (Schenk).
Its remarkable efficacy in treating immune‐related and inflammatory disorders has garnered …

[HTML][HTML] Bioinformatics analysis of pathways of renal infiltrating macrophages in different renal disease models

YC Cheuk, P Zhang, S Xu, J Wang, T Chen… - Translational …, 2021 - ncbi.nlm.nih.gov
Background Recent studies have suggested that macrophages are significantly involved in
different renal diseases. However, the role of these renal infiltrating macrophages has not …

Anti-inflammatory, Anti-bacterial and Anti-oxidant Activities for Subcritical Extract of Chamaecyparis obtusa

JE Kim, MJ Kim, JY Moon, JM Kim, TH Oh… - Journal of the Korean …, 2024 - koreascience.kr
In this study, the anti-inflammatory, anti-bacterial and anti-oxidative activities of subcritical
water extract from Chamaecyparis obtusa leaves was compared with hot water extract. The …