Rosemary (Rosmarinus officinalis [family Lamiaceae]), an herb of economic and gustatory
repute, is employed in traditional medicines in many countries. Rosemary contains carnosic …

Neurodegenerative diseases (NDDs) are leading causes of death and morbidity in the
elderly worldwide. From the mechanistic/pathological view, oxidative stress, inflammation …

Regulated cell death (RCD) is a ubiquitous process in living organisms that is essential for
tissue homeostasis or to restore biological balance under stress. Over the decades, various …

Neurodegenerative diseases are characterized by the progressive loss of neurons and
intricate interactions between different cell types within the affected regions. Reliable …

Neuroinflammation is one of the host defensive mechanisms through which the nervous
system protects itself from pathogenic and or infectious insults. Moreover, neuroinflammation …

Abstract In the Central Nervous System (CNS), neuroinflammation orchestrated by microglia
and astrocytes is an innate immune response to counteract stressful and dangerous insults …

The inflammasome regulates innate immunity by serving as a signaling platform. The Nod‑
like receptor protein 3 (NLRP3) inflammasome, equipped with NLRP3, the adaptor protein …

In tauopathies, abnormal deposition of intracellular tau protein followed by gradual elevation
of tau in cerebrospinal fluids and neuronal loss has been documented, however, the …

Multiple sclerosis (MS) is an autoimmune demyelinating neurodegenerative disease of the
central nervous system (CNS) due to injury of the myelin sheath by immune cells. The …

Alpha-Synuclein (α-Syn) is one of the most important molecules involved in the
pathogenesis of Parkinson's disease and related disorders, synucleinopathies, but also in …