Cell adhesion molecules and their roles and regulation in the immune and tumor microenvironment

H Harjunpää, M Llort Asens, C Guenther… - Frontiers in …, 2019 - frontiersin.org
The immune system and cancer have a complex relationship with the immune system
playing a dual role in tumor development. The effector cells of the immune system can …

The role of helper T cells in psoriasis

P Hu, M Wang, H Gao, A Zheng, J Li, D Mu… - Frontiers in …, 2021 - frontiersin.org
Psoriasis is a complex, chronic relapsing and inflammatory skin disorder with a prevalence
of approximately 2% in the general population worldwide. Psoriasis can be triggered by …

Role of regulatory T cells in psoriasis pathogenesis and treatment

L Nussbaum, YL Chen, GS Ogg - British Journal of Dermatology, 2021 - academic.oup.com
Psoriasis is a chronic inflammatory disease with a strong genetic component that can be
triggered by environmental factors. Disease pathogenesis is mainly driven by type 1 and …

Scanning the immunopathogenesis of psoriasis

A Chiricozzi, P Romanelli, E Volpe… - International journal of …, 2018 - mdpi.com
Psoriasis is a chronic inflammatory skin disease, the immunologic model of which has been
profoundly revised following recent advances in the understanding of its pathophysiology. In …

The inflammatory response in psoriasis: a comprehensive review

Y Deng, C Chang, Q Lu - Clinical reviews in allergy & immunology, 2016 - Springer
Psoriasis is a chronic inflammatory autoimmune disease characterized by an excessively
aberrant hyperproliferation of keratinocytes. The pathogenesis of psoriasis is complex and …

The functional crosstalk between myeloid-derived suppressor cells and regulatory T cells within the immunosuppressive tumor microenvironment

M Haist, H Stege, S Grabbe, M Bros - Cancers, 2021 - mdpi.com
Simple Summary Immunotherapy improved the therapeutic landscape for patients with
advanced cancer diseases. However, many patients do not benefit from immunotherapy …

New insights of T cells in the pathogenesis of psoriasis

Y Cai, C Fleming, J Yan - Cellular & molecular immunology, 2012 - nature.com
Psoriasis is one of the most common immune-mediated chronic, inflammatory skin diseases
characterized by hyperproliferative keratinocytes and infiltration of T cells, dendritic cells …

Loss of BAP1 expression is associated with an immunosuppressive microenvironment in uveal melanoma, with implications for immunotherapy development

CR Figueiredo, H Kalirai, JJ Sacco… - The Journal of …, 2020 - Wiley Online Library
Immunotherapy using immune checkpoint inhibitors (ICIs) induces durable responses in
many metastatic cancers. Metastatic uveal melanoma (mUM), typically occurring in the liver …

[HTML][HTML] TSG-6 released from intradermally injected mesenchymal stem cells accelerates wound healing and reduces tissue fibrosis in murine full-thickness skin …

Y Qi, D Jiang, A Sindrilaru, A Stegemann… - Journal of Investigative …, 2014 - Elsevier
Proper activation of macrophages (Mφ) in the inflammatory phase of acute wound healing is
essential for physiological tissue repair. However, there is a strong indication that robust Mφ …

TGF-β: the sword, the wand, and the shield of FOXP3+ regulatory T cells

DQ Tran - Journal of molecular cell biology, 2012 - academic.oup.com
Since its rediscovery in the mid-1990s, FOXP3+ regulatory T cells (Tregs) have climbed the
rank to become commander-in-chief of the immune system. They possess diverse power …