[HTML][HTML] Focused ultrasound for opening blood-brain barrier and drug delivery monitored with positron emission tomography

WM Arif, PH Elsinga, C Gasca-Salas, M Versluis… - Journal of controlled …, 2020 - Elsevier
Focused ultrasound (FUS) is a minimally-invasive technology used for treatment of many
diseases, including diseases related to the colon, uterus, prostate, and brain. Although it has …

[HTML][HTML] 18F-labeled radiopharmaceuticals for the molecular neuroimaging of amyloid plaques in Alzheimer's disease

L Filippi, A Chiaravalloti, O Bagni… - American Journal of …, 2018 - ncbi.nlm.nih.gov
Alzheimer's disease (AD) is the most common cause of dementia in the elderly, with
tremendous impact on the affected individuals and the society. Definitive diagnosis can be …

[HTML][HTML] Amyloid imaging: poised for integration into medical practice

K Anand, M Sabbagh - Neurotherapeutics, 2017 - Elsevier
Amyloid imaging represents a significant advance as an adjunct in the diagnosis of
Alzheimer's disease (AD) because it is the first imaging modality that identifies in vivo …

Fluselenamyl: a novel benzoselenazole derivative for PET detection of amyloid plaques (Aβ) in Alzheimer's disease

GSM Sundaram, DD Dhavale, JL Prior, P Yan… - Scientific reports, 2016 - nature.com
Abstract Fluselenamyl (5), a novel planar benzoselenazole shows traits desirable of
enabling noninvasive imaging of Aβ pathophysiology in vivo; labeling of both diffuse (an …

[18F] Amylovis as a Potential PET Probe for β-Amyloid Plaque: Synthesis, in Silico, in vitro and in vivo Evaluations

S Rivera-Marrero, L Fernández-Maza… - Current …, 2019 - ingentaconnect.com
Background: Alzheimer's disease (AD) is the most common form of dementia. Neuroimaging
methods have widened the horizons for AD diagnosis and therapy. The goals of this work …

Medicinal (Radio) Chemistry: Building Radiopharmaceuticals for the Future

MSO Pijeira, PSG Nunes, SL Chaviano… - Current Medicinal …, 2024 - benthamdirect.com
Radiopharmaceuticals are increasingly playing a leading role in diagnosing, monitoring,
and treating disease. In comparison with conventional pharmaceuticals, the development of …

Preliminary PET Study of 18F-FC119S in Normal and Alzheimer's Disease Models

SJ Oh, MH Kim, SJ Han, KJ Kang, IO Ko… - Molecular …, 2017 - ACS Publications
To evaluate the efficacy of 18F-FC119S as a positron emission tomography (PET)
radiopharmaceutical for the imaging of Alzheimer's disease (AD), we studied the drug …

Radiotracers for amyloid imaging in neurodegenerative disease: state-of-the-art and novel concepts

A Cistaro, P Alongi, F Caobelli… - Current medicinal …, 2018 - ingentaconnect.com
The pathological accumulation of different peptides is the common base of many
neurodegenerative processes, such as Alzheimer's disease (AD). AD is characterized by …

[PDF][PDF] Die 18F-Florbetaben-Amyloid-PET-CT im Vergleich mit etablierten Diagnostikmethoden in der Frühdiagnostik bei M. Alzheimer

T Germann - 2022 - edoc.ub.uni-muenchen.de
Für Morbus Alzheimer (M. Alzheimer), der weltweit über 60% der Demenzerkrankungen
ausmacht [3], gilt, dass sich die neuropathologischen Veränderungen im Gehirn der …

SMALL MEDICAL CYCLOTRON PRODUCED RADIOISOTOPES: FROM CLASSIC TO NOVEL RADIOTRACERS

A CIUCA, CP MAIREAN, AF SPAC… - The Medical-Surgical …, 2019 - revmedchir.ro
Positron emission tomography (PET) has become a widespread and indispensable tool for
non-invasive oncological, cardiological and neurological diagnosis. With its increase use …