Vitamin D and its analogs as anticancer and anti-inflammatory agents

J Chen, Z Tang, AT Slominski, W Li… - European journal of …, 2020 - Elsevier
Vitamin D3 is the precursor of the steroid hormone calcitriol (1α, 25-dihydroxyvitamin D3), a
potent agonist of the transcription factor vitamin D receptor (VDR). Calcitriol has received …

Functional effects of vitamin D: From nutrient to immunomodulator

MR Meza-Meza, AI Ruiz-Ballesteros… - Critical reviews in …, 2022 - Taylor & Francis
Vitamin D can be obtained from the endogenous synthesis in the epidermis by exposure to
UVB light, and from foods and supplements in the form of ergocalciferol (vitamin D2) and …

Expression of asprosin in rat hepatic, renal, heart, gastric, testicular and brain tissues and its changes in a streptozotocin-induced diabetes mellitus model

N Kocaman, T Kuloğlu - Tissue and Cell, 2020 - Elsevier
In this study, we aimed to investigate the presence of asprosin (ASP) in the liver, kidneys,
heart, stomach, testicles and brain and to determine the serum and tissue asprosin levels in …

Vitamin D receptor prevents tumour development by regulating the Wnt/β-catenin signalling pathway in human colorectal cancer

J Yu, Q Sun, Y Hui, J Xu, P Shi, Y Chen, Y Chen - BMC cancer, 2023 - Springer
Background Colorectal cancer (CRC) is a common disease threatening human lives
worldwide, and vitamin D receptor (VDR) contributes protective roles in this disease …

Vitamin D receptor expression and its clinical significance in papillary thyroid cancer

MJ Kim, D Kim, JS Koo, JH Lee… - Technology in Cancer …, 2022 - journals.sagepub.com
Objective: This study aimed to evaluate the association between vitamin D receptor (an
essential component in the vitamin D signaling pathway) and serum vitamin D as well as its …

[HTML][HTML] Association of vitamin D receptor polymorphisms with colorectal cancer susceptibility: A systematic meta-analysis

M Yang, W Ji, N Xu, J Gu, X Guo, L Zhang - Medicine, 2023 - journals.lww.com
Background: Recent studies have reported an association between vitamin D receptor
(VDR) polymorphisms and colorectal cancer (CRC) risk; however, the results are …

Vitamin D Status, Cdx2 Genotype, and Colorectal Cancer Survival: Population-Based Patient Cohort

T Gwenzi, P Schrotz-King, B Schöttker, M Hoffmeister… - Nutrients, 2023 - mdpi.com
According to recent evidence, the prognostic value of Vitamin D (VitD) status for colorectal
cancer (CRC) patients might be confined to patients with the GG genotype of Cdx2, a …

Analysis of Potential Vitamin D Molecule Biomarkers: Association of Calcitriol and Its Hydroxylation Efficiency Ratio with Cardiovascular Disease Risk in Rheumatoid …

M Rivera-Escoto, B Campos-López… - Biomedicines, 2024 - mdpi.com
Rheumatoid arthritis (RA) is a multifactorial autoimmune disease in which hypovitaminosis D
by calcidiol quantification has been associated with disease severity. However, other vitamin …

维生素D3在移植免疫中的应用进展.

夏征, 周林 - Organ Transplantation/Qi Guan Yi Zhi, 2023 - search.ebscohost.com
维生素D3 是维持人体正常生理功能的重要维生素, 其代谢物及类似物具有强大的抗炎活性.
维生素D3 可在人体内活化转化为类固醇激素1α, 25-二羟维生素D3, 而1α, 25-二羟维生素D3 …

The clinical significance of VDR and WIFI downregulation in colorectal cancer tissue

SM Mir, A Nezhadi, SS Tehrani, Z Jamalpoor - Gene Reports, 2020 - Elsevier
Abstract Background Activation of the Wnt/β catenin signaling pathway is the first event in
the majority of colorectal cancers. Wnt inhibitory factor 1 (WIF1) inhibits the activity Wnt/β …