The important role of GH in the control of mammalian longevity was first deduced from
extended longevity of mice with genetic GH deficiency (GHD) or GH resistance. Mice with …

Secreted by the anterior pituitary gland, growth hormone (GH) is a peptide that plays a
critical role in regulating cell growth, development, and metabolism in multiple targeted …

Objective To study the effect of aging and granulosa cell growth hormone receptor (GHR)
expression, and the effect of growth hormone (GH) co-treatment during IVF on receptor …

Increases in delayed childbearing worldwide have elicited the need for a better
understanding of the biological underpinnings and implications of age-related infertility. In …

Caloric restriction (CR) increases the preservation of the ovarian primordial follicular
reserve, which can potentially delay menopause. Rapamycin also increases preservation on …

Senescent cells are in a cell cycle arrest state and accumulate with aging and obesity,
contributing to a chronic inflammatory state. Treatment with senolytic drugs dasatinib and …

Abstract Calorie restriction (CR)(25–40%) is the most commonly studied strategy for
curtailing age-related disease and has also been found to extend reproductive lifespan in …

Growth hormone (GH) has been used as a co-gonadotrophin in assisted reproduction,
particularly in poor ovarian responders. The application of GH has been alleged to activate …

Growth Hormone (GH) has been considered as a therapeutic option to increase the number
of growing follicles during Assisted Reproductive Technology (ART) for more than 30 years …

Calorie restriction (CR) is an intervention that promotes longevity and preserves the ovarian
reserve. Some studies have observed that the positive impacts of CR can be linked to …