Tripartite efflux pumps and the related type 1 secretion systems (T1SSs) in Gram-negative
organisms are diverse in function, energization, and structural organization. They form …

Although Escherichia coli can be an innocuous resident of the gastrointestinal tract, it also
has the pathogenic capacity to cause significant diarrheal and extraintestinal diseases …

Most Escherichia coli strains live harmlessly in the intestines and rarely cause disease in
healthy individuals. Nonetheless, a number of pathogenic strains can cause diarrhea or …

Whole-genome sequencing has been skewed toward bacterial pathogens as a
consequence of the prioritization of medical and veterinary diseases. However, it is …

The MacB ABC transporter forms a tripartite efflux pump with the MacA adaptor protein and
TolC outer membrane exit duct to expel antibiotics and export virulence factors from Gram …

In gram-negative bacteria, type I secretion is carried out by a translocator made up of three
proteins that span the cell envelope. One of these proteins is a specific outer membrane …

Enteroaggregative Escherichia coli (EAEC) represents a heterogeneous group of E. coli
strains. The pathogenicity and clinical relevance of these bacteria are still controversial. In …

MacB is an ABC transporter that collaborates with the MacA adaptor protein and TolC exit
duct to drive efflux of antibiotics and enterotoxin STII out of the bacterial cell. Here we …

Diarrheagenic Escherichia coli have developed different strategies for establishment of
infection in their host. Understanding these pathogenic mechanisms has led to the …

Autoaggregation, adherence between identical bacterial cells, is important for colonization,
kin and kind recognition, and survival of bacteria. It is directly mediated by specific …