Biological activities of hydrazone derivatives

S Rollas, Ş Güniz Küçükgüzel - Molecules, 2007 - mdpi.com
There has been considerable interest in the development of novel compounds with
anticonvulsant, antidepressant, analgesic, antiinflammatory, antiplatelet, anti-malarial …

Thiourea, triazole and thiadiazine compounds and their metal complexes as antifungal agents

E Rodriguez-Fernandez, JL Manzano, JJ Benito… - Journal of inorganic …, 2005 - Elsevier
Many currently available antifungal and antibacterial agents have undesirable toxic effects,
and a wide spread use of these drugs has lead to rapid development of drug resistant …

Repositioning of acefylline as anti-cancer drug: Synthesis, anticancer and computational studies of azomethines derived from acefylline tethered 4-amino-3-mercapto …

I Shahzadi, AF Zahoor, B Tüzün, A Mansha, MN Anjum… - Plos one, 2022 - journals.plos.org
Novel azomethines derived from acefylline tethered triazole hybrids (7a-k) have been
synthesized and evaluated against human liver cancer cell line (Hep G2) using MTT assay …

Evaluation of DNA binding, DNA cleavage, protein binding and in vitro cytotoxic activities of bivalent transition metal hydrazone complexes

P Krishnamoorthy, P Sathyadevi, AH Cowley… - European journal of …, 2011 - Elsevier
Abstract Divalent Co, Ni and Cu hydrazone complexes containing [N′-(phenyl (pyridine-2-
yl) methylidene) benzohydrazide] ligand were synthesised and characterised. Interactions of …

Synthesis and biological activities of diflunisal hydrazide–hydrazones

SG Küçükgüzel, A Mazi, F Sahin, S Öztürk… - European journal of …, 2003 - Elsevier
Several diflunisal hydrazide–hydrazone derivatives namely 2′, 4′-difluoro-4-
hydroxybiphenyl-3-carboxylic acid [(5-nitro-2-furyl/substitutedphenyl) methylene] hydrazide …

Synthesis and characterization of novel hydrazide–hydrazones and the study of their structure–antituberculosis activity

KK Bedia, O Elçin, U Seda, K Fatma, S Nathaly… - European journal of …, 2006 - Elsevier
A series of hydrazide–hydrazones, based on a series of 4-substituted benzoic acid, were
synthesized, and their structures were elucidated and screened for the antituberculosis …

Synthesis of some novel thiourea derivatives obtained from 5-[(4-aminophenoxy) methyl]-4-alkyl/aryl-2, 4-dihydro-3H-1, 2, 4-triazole-3-thiones and evaluation as …

İ Küçükgüzel, E Tatar, ŞG Küçükgüzel, S Rollas… - European journal of …, 2008 - Elsevier
As a continuation of our previous efforts on N-alkyl/aryl-N′-[4-(4-alkyl/aryl-2, 4-dihydro-3H-
1, 2, 4-triazole-3-thione-5-yl) phenyl] thioureas 1–19 and N-alkyl/aryl-N′-[4-(3-aralkylthio-4 …

Some 3-thioxo/alkylthio-1, 2, 4-triazoles with a substituted thiourea moiety as possible antimycobacterials

I Küçükgüzel, SG Küçükgüzel, S Rollas… - Bioorganic & medicinal …, 2001 - Elsevier
A series of novel N-alkyl/aryl-N′-[4-(4-alkyl/aryl-2, 4-dihydro-3H-1, 2, 4-triazole-3-thione-5-
yl) phenyl] thioureas 1–19 and three S-alkylated representatives of the former, N-alkyl/aryl …

Synthesis of new hydrazones using a biodegradable catalyst, their biological evaluations and molecular modeling studies (Part-II)

SN Mali, A Pandey - Journal of Computational Biophysics and …, 2022 - World Scientific
Hydrazones typically have an azomethine '–NHN= CH group'which is crucial for varieties of
pharmacological activities. In this study, we have synthesized a set of 15 new hydrazones …

New Cu (II), Co (II), Ni (II) complexes with aroyl-hydrazone based ligand. Synthesis, spectroscopic characterization and in vitro antibacterial evaluation

MV Angelusiu, SF Barbuceanu, C Draghici… - European journal of …, 2010 - Elsevier
A new aroyl-hydrazone, N-(2-pyridinecarbaldehyde)-N′-[4-(4-chloro-phenylsulfonyl)
benzoyl]-hydrazone (L) and its Cu (II), Co (II) and Ni (II) complexes have been prepared. The …