Intracerebral hemorrhage (ICH) induces high mortality and disability. Neuronal death is the
principal factor to unfavourable prognosis in ICH. However, the mechanisms underlying this …

Disabilities are estimated to occur in approximately 2% of survivors of traumatic brain injury
(TBI) worldwide, and disability may persist even decades after brain injury. Facilitation or …

Farnesoid X receptor (FXR) is a nuclear hormone receptor involved in bile acid synthesis
and homeostasis. Dysfunction of FXR is involved in cholestasis and atherosclerosis. FXR is …

Norepinephrine plays an important role in motor functional recovery after a brain injury
caused by ferrous chloride. Inhibition of norepinephrine release by clonidine is correlated …

The brain cortex is the structure that is typically injured in traumatic brain injury (TBI) and is
anatomically connected with other brain regions, including the striatum and hypothalamus …

Noradrenaline (NA) levels are altered during the first hours and several days after cortical
injury. NA modulates motor functional recovery. The present study investigated whether iron …

The sensorimotor cortex and the cerebellum are interconnected by the
corticopontocerebellar (CPC) pathway and by neuronal groups such as the serotonergic …

Traumatic brain injury (TBI, neurotrauma) is an urgent biomedical concern with high
prevalence and mortality risks. Probing TBI mechanisms in traditional (eg, rodent) animal …

Brain injury leads to an excitatory phase followed by an inhibitory phase in the brain. The
clinical sequelae caused by cerebral injury seem to be a response to remote functional …

Toluene, found in glues and cleaners, is among the inhalants most commonly abused by
workers and young drug addicts. In this study, we examined the changes in sleep patterns …