It has been almost a decade since the first next generation sequencing (NGS) technologies
emerged and quickly changed the way genetic research is conducted. Today, full genomes …

The prevention and diagnosis of sudden cardiac death (SCD) are among the most important
keystones and challenges in clinical and forensic practice. However, the diagnostic value of …

In many SCD cases, in particular in pediatric age, autopsy can be completely negative and
then a post-mortem genetic testing (molecular autopsy) is indicated. In NGS era finding …

Background In sudden, unexpected, non-traumatic death in young individuals, structural
abnormalities of the heart are frequently identified at autopsy. However, the findings may be …

Aims Preventing sudden cardiac death (SCD) due to acute myocardial infarction (MI) in
previously healthy patients is challenging. Proteomic analysis may lead to an understanding …

OBJECTIVE To evaluate a group of related Rhodesian Ridgebacks with a family history of
sudden death for the presence of arrhythmia and to identify possible patterns of disease …

Background More than half of cardiovascular mortality occurs outside the hospital, mainly
due to consistently low survival rates from out-of-hospital cardiac arrest. Methods This is a …

Introduction Sudden unexpected death syndrome (SUDS) is an important cause of death in
young healthy adults with a high incident rate in Southeast Asia; however, there are no …

Abstract Purpose of Review Genetic testing has become an important element in the care of
patients with inherited cardiac conditions (ICCs). The purpose of this review is to provide …

Background Juvenile sudden cardiac death (SCD) remains unexplained in approximately
40% of cases, leading to a significant emotional burden for the victims' families and society …