Mechanisms of DNA damage, repair, and mutagenesis
N Chatterjee, GC Walker - Environmental and molecular …, 2017 - Wiley Online Library
Living organisms are continuously exposed to a myriad of DNA damaging agents that can
impact health and modulate disease‐states. However, robust DNA repair and damage …
impact health and modulate disease‐states. However, robust DNA repair and damage …
Molecular mechanisms of ultraviolet radiation‐induced DNA damage and repair
RP Rastogi, null Richa, A Kumar… - Journal of nucleic …, 2010 - Wiley Online Library
DNA is one of the prime molecules, and its stability is of utmost importance for proper
functioning and existence of all living systems. Genotoxic chemicals and radiations exert …
functioning and existence of all living systems. Genotoxic chemicals and radiations exert …
TP 53 mutations in human cancer: database reassessment and prospects for the next decade
B Leroy, M Anderson, T Soussi - Human mutation, 2014 - Wiley Online Library
More than 50% of human tumors carry TP 53 gene mutations and in consequence more
than 45,000 somatic and germline mutations have been gathered in the UMD TP 53 …
than 45,000 somatic and germline mutations have been gathered in the UMD TP 53 …
UV-induced DNA damage and repair: a review
Increases in ultraviolet radiation at the Earth's surface due to the depletion of the
stratospheric ozone layer have recently fuelled interest in the mechanisms of various effects …
stratospheric ozone layer have recently fuelled interest in the mechanisms of various effects …
Mutations induced by ultraviolet light
The different ultraviolet (UV) wavelength components, UVA (320–400nm), UVB (280–
320nm), and UVC (200–280nm), have distinct mutagenic properties. A hallmark of UVC and …
320nm), and UVC (200–280nm), have distinct mutagenic properties. A hallmark of UVC and …
Ultraviolet radiation-mediated damage to cellular DNA
Emphasis is placed in this review article on recent aspects of the photochemistry of cellular
DNA in which both the UVB and UVA components of solar radiation are implicated …
DNA in which both the UVB and UVA components of solar radiation are implicated …
[图书][B] Nucleic acids in chemistry and biology
GM Blackburn - 2006 - books.google.com
The structure, function and reactions of nucleic acids are central to molecular biology and
are crucial for the understanding of complex biological processes involved. Revised and …
are crucial for the understanding of complex biological processes involved. Revised and …
[HTML][HTML] Light-driven enzymatic catalysis of DNA repair: a review of recent biophysical studies on photolyase
S Weber - Biochimica et Biophysica Acta (BBA)-Bioenergetics, 2005 - Elsevier
More than 50 years ago, initial experiments on enzymatic photorepair of ultraviolet (UV)-
damaged DNA were reported [Proc. Natl. Acad. Sci. USA 35 (1949) 73]. Soon after this …
damaged DNA were reported [Proc. Natl. Acad. Sci. USA 35 (1949) 73]. Soon after this …
p53 and the pathogenesis of skin cancer
CL Benjamin, HN Ananthaswamy - Toxicology and applied pharmacology, 2007 - Elsevier
The p53 tumor suppressor gene and gene product are among the most diverse and complex
molecules involved in cellular functions. Genetic alterations within the p53 gene have been …
molecules involved in cellular functions. Genetic alterations within the p53 gene have been …
Early events of DNA photodamage
WJ Schreier, P Gilch, W Zinth - Annual review of physical …, 2015 - annualreviews.org
Ultraviolet (UV) radiation is a leading external hazard to the integrity of DNA. Exposure to UV
radiation triggers a cascade of chemical reactions, and many molecular products …
radiation triggers a cascade of chemical reactions, and many molecular products …