Membrane rafts: portals for viral entry

I Ripa, S Andreu, JA López-Guerrero… - Frontiers in …, 2021 - frontiersin.org
Membrane rafts are dynamic, small (10–200 nm) domains enriched with cholesterol and
sphingolipids that compartmentalize cellular processes. Rafts participate in roles essential to …

Virus entry, assembly, budding, and membrane rafts

N Chazal, D Gerlier - Microbiology and molecular biology reviews, 2003 - Am Soc Microbiol
As intracellular parasites, viruses rely heavily on the use of numerous cellular machineries
for completion of their replication cycle. The recent discovery of the heterogeneous …

Role of lipids in virus replication

M Lorizate, HG Kräusslich - Cold Spring Harbor …, 2011 - cshperspectives.cshlp.org
Viruses intricately interact with and modulate cellular membranes at several stages of their
replication, but much less is known about the role of viral lipids compared to proteins and …

Remorin, a Solanaceae Protein Resident in Membrane Rafts and Plasmodesmata, Impairs Potato virus X Movement

S Raffaele, E Bayer, D Lafarge, S Cluzet… - The Plant …, 2009 - academic.oup.com
Remorins (REMs) are proteins of unknown function specific to vascular plants. We have
used imaging and biochemical approaches and in situ labeling to demonstrate that REM …

The many mechanisms of viral membrane fusion proteins

LJ Earp, SE Delos, HE Park, JM White - Membrane trafficking in viral …, 2005 - Springer
Every enveloped virus fuses its membrane with a host cell membrane, thereby releasing its
genome into the cytoplasm and initiating the viral replication cycle. In each case, one or a …

Cholesterol and the interaction of proteins with membrane domains

RM Epand - Progress in lipid research, 2006 - Elsevier
Cholesterol is not uniformly distributed in biological membranes. One of the factors
influencing the formation of cholesterol-rich domains in membranes is the unequal lateral …

The membrane-proximal external region of the human immunodeficiency virus type 1 envelope: dominant site of antibody neutralization and target for vaccine design

M Montero, NE van Houten, X Wang… - … and molecular biology …, 2008 - Am Soc Microbiol
Enormous efforts have been made to produce a protective vaccine against human
immunodeficiency virus type 1; there has been little success. However, the identification of …

Antiviral effects of statins

AM Gorabi, N Kiaie, V Bianconi, T Jamialahmadi… - Progress in lipid …, 2020 - Elsevier
Introducing statins as possible widely-available drugs for the treatment of viral infections
requires an in depth review of their antiviral properties. Despite some inconsistency, a large …

Lipid rafts and HIV pathogenesis: virion-associated cholesterol is required for fusion and infection of susceptible cells

Z Liao, DR Graham, JEK Hildreth - AIDS research and human …, 2003 - liebertpub.com
We have shown that HIV budding occurs at cholesterol-rich membrane microdomains called
lipid rafts (Nguyen and Hildreth, J Virol 2000; 74: 3264-3272). This observation prompted us …

Lipids and membrane microdomains in HIV-1 replication

AA Waheed, EO Freed - Virus research, 2009 - Elsevier
Several critical steps in the replication cycle of human immunodeficiency virus type 1 (HIV-1)–
entry, assembly and budding–are complex processes that take place at the plasma …