Trifolirhizin reduces osteoclast formation and prevents inflammatory osteolysis by inhibiting RANKL‐induced activation of NF‐κB and MAPK signaling pathways and …
J Huang, D Song, M Xu, K Gan, C Wang… - Phytotherapy …, 2024 - Wiley Online Library
Inflammatory osteolysis is often caused by the excessive activation of osteoclasts stimulated
by bacterial products such as lipopolysaccharide. The natural flavonoid trifolirhizin (TRI) has …
by bacterial products such as lipopolysaccharide. The natural flavonoid trifolirhizin (TRI) has …
Tubulin Homologs in Bacteria and Archaea
NA Rumyantseva, DM Golofeeva, AA Khasanova… - Microbiology, 2024 - Springer
While cytoskeletal proteins have long been considered to be present only in eukaryotes, but
not in prokaryotes, homologs of the major cytoskeletal proteins, including tubulin, have been …
not in prokaryotes, homologs of the major cytoskeletal proteins, including tubulin, have been …
[HTML][HTML] Pharmacophore, QSAR, molecular docking, molecular dynamics and ADMET study of trisubstituted benzimidazole derivatives as potent anti-tubercular agents
A Moulishankar, T Sundarrajan - Chemical Physics Impact, 2024 - Elsevier
The objective of this study was to develop and verify a QSAR model for predicting the
antitubercular effects of trisubstituted benzimidazole derivatives. For this study, 50 …
antitubercular effects of trisubstituted benzimidazole derivatives. For this study, 50 …
Staphylococcus aureus major cell division protein FtsZ assembly is inhibited by silibinin, a natural flavonolignan that also blocked bacterial growth and biofilm …
P Basak, DG Dastidar, D Ghosh, T Chakraborty… - International Journal of …, 2024 - Elsevier
The bacterial cell division protein FtsZ has been considered a potential therapeutic target
due to its rapid treadmilling that induces cellular wall construction in bacteria. The current …
due to its rapid treadmilling that induces cellular wall construction in bacteria. The current …
Discovery of novel bioactive compounds in Catharanthus roseus exhibiting anti-angiogenic activity against VEGFR-2 TKD for Glioblastoma tumor growth suppression
A Senrung, D Kumar, N Bhardwaj… - Biomedical and …, 2024 - pubs.thesciencein.org
The progression of Glioblastoma (GBM) relies heavily on angiogenesis, the formation of new
blood vessels, facilitated by proangiogenic factors like vascular endothelial growth factor …
blood vessels, facilitated by proangiogenic factors like vascular endothelial growth factor …
The antioxidant and antimicrobial activity of ethanolic extract in roots, stems, and leaves of three commercial Cymbopogon species
Background Cymbopogon is a member of the family Poaceae and has been explored for its
phytochemicals and bioactivities. Although the antimicrobial activities of Cymbopogon spp …
phytochemicals and bioactivities. Although the antimicrobial activities of Cymbopogon spp …
Учредители: Федеральный исследовательский центр" Фундаментальные основы биотехнологии" РАН, Российская академия наук, Российская академия наук …
НА РУМЯНЦЕВА, ДМ ГОЛОФЕЕВА… - …, 2024 - elibrary.ru
Долгое время считали, что белки цитоскелета отсутствуют у прокариот и имеются
только у эукариот, однако за последние 30 лет у бактерий и архей обнаружены …
только у эукариот, однако за последние 30 лет у бактерий и архей обнаружены …