Long-term depression (LTD) in the CNS has been the subject of intense investigation as a
process that may be involved in learning and memory and in various pathological …

Since the observation that nitric oxide (NO) can act as an intercellular messenger in the
brain, the past 25 years have witnessed the steady accumulation of evidence that it acts pre …

It has been 30 years since the discovery that repeated electrical stimulation of neural
pathways can lead to long-term potentiation in hippocampal slices. With its relevance to …

Spatio-temporal configurations of distributed activity in the brain is thought to contribute to
the coding of neuronal information and synaptic contacts between nerve cells could play a …

Vesicular release of neurotransmitter is the universal output signal of neurons in the brain. It
is generally believed that fast transmitter release is restricted to nerve terminals that contact …

Long-term synaptic plasticity is a major cellular substrate for learning, memory, and
behavioral adaptation. Although early examples of long-term synaptic plasticity described a …

Therapeutic hypothermia at 32-34° C during or after cerebral ischaemia is neuroprotective.
However, peripheral cold sensor-triggered hypothermia is ineffective and evokes vigorous …

The complex relationship between specific hippocampal oscillation frequency deficit and
cognitive dysfunction in the ischemic brain is unclear. Here, using a mouse two-vessel …

For many years part of the limbic system, the hippocampus, has been associated with
memory. The discovery of cooperativity in the nerve fibres of this part of the brain, where …

Recent results suggest that long-lasting potentiation at hippocampal synapses involves the
rapid formation of clusters or puncta of presynaptic as well as postsynaptic proteins, both of …