Antidiabetic medicinal plants as a source of alpha glucosidase inhibitors

W Benalla, S Bellahcen… - Current diabetes …, 2010 - ingentaconnect.com
The aim of this study is to collate all available data on antidiabetic plants that inhibit alpha
glucosidase, reported mainly by Medline (PubMed) these last years. In the present study …

Isolated compounds from natural products with potential antidiabetic activity-a systematic review

ACM Munhoz, TS Frode - Current diabetes reviews, 2018 - benthamdirect.com
Background: Worldwide, Type 2 diabetes has become a growing health problem. While
many research articles in the field of ethnopharmacology have focused on the antidiabetic …

[图书][B] Herbalism, phytochemistry and ethnopharmacology

A Singh - 2011 - books.google.com
Bridging the gap between the ancient art of herbalism and the emerging sciences of
ethnopharmocology and phytopharmacotherapy, this book highlights the major …

Design and synthesis of sulfonium derivatives: a novel class of α-glucosidase inhibitors with potent in vivo antihyperglycemic activities

L Lu, J Chen, W Tao, Z Wang, D Liu… - Journal of Medicinal …, 2023 - ACS Publications
We report the first attempt of double-spot structural modification on a side-chain moiety of
sulfonium-type α-glucosidase inhibitors isolated from genus Salacia. A series of sulfonium …

Synthesis and biological activity of naturally occurring α-glucosidase inhibitors

DJ Wardrop, SL Waidyarachchi - Natural Product Reports, 2010 - pubs.rsc.org
Covering: 2005 to the end of 2009 In addition to their clinical importance in the treatment of
type II diabetes, α-glucosidase inhibitors have attracted considerable attention from the …

Heterocyclic compounds: effective α-amylase and α-glucosidase inhibitors

M Saeedi, A Hadjiakhondi… - Current Topics in …, 2017 - ingentaconnect.com
Diabetes Mellitus (DM) is a metabolic disease characterized by high blood sugar levels.
Recently, it has emerged as an important and global health problem with long-term …

Modulation of starch digestion for slow glucose release through “toggling” of activities of mucosal α-glucosidases

BH Lee, R Eskandari, K Jones, KR Reddy… - Journal of Biological …, 2012 - ASBMB
Starch digestion involves the breakdown by α-amylase to small linear and branched malto-
oligosaccharides, which are in turn hydrolyzed to glucose by the mucosal α-glucosidases …

Naturally occurring sulfonium-ion glucosidase inhibitors and their derivatives: a promising class of potential antidiabetic agents

S Mohan, R Eskandari, BM Pinto - Accounts of chemical research, 2014 - ACS Publications
In humans, four different enzymes mediate the digestion of ingested carbohydrates. First
salivary and pancreatic α-amylases, the two endoacting retaining glucosidases, break down …

[图书][B] Plants with anti-diabetes mellitus properties

A Subramoniam - 2016 - taylorfrancis.com
The incidence and severity of diabetes mellitus is increasing worldwide, presenting a
significant burden to society both in economic terms and overall well-being. Fortunately, time …

Isolation, structure identification and SAR studies on thiosugar sulfonium salts, neosalaprinol and neoponkoranol, as potent α-glucosidase inhibitors

W Xie, G Tanabe, J Akaki, T Morikawa… - Bioorganic & medicinal …, 2011 - Elsevier
Two hitherto missing members of sulfonium salts family in Salacia genus plants as a new
class of α-glucosidase inhibitors, neoponkoranol (7) and neosalaprinol (8), were isolated …