Surgical resection remains the mainstay of treatment for patients with glioma of any grade.
Maximal resection of the tumour is central to achieving long-term disease control; however …

Diffuse low-grade glioma grows, migrates along white matter tracts, and progresses to high-
grade glioma. Rather than a “wait and see” policy, an aggressive attitude is now …

PURPOSE In patients with diffuse low-grade glioma (LGG), the extent of surgical tumor
resection (EOR) has a controversial role, in part because a randomized clinical trial with …

Background Extensive resections in low-grade glioma (LGG) are associated with improved
overall survival (OS). However, World Health Organization (WHO) classification of gliomas …

Background Infiltrating low-grade gliomas (LGG; WHO grade 2) typically present with
seizures in young adults. LGGs grow continuously and usually transform to higher grade of …

Background Total or subtotal surgical resection of WHO grade II glioma (diffuse low-grade
glioma, DLGG) can significantly increase survival. Moreover, a supratotal resection, ie, an …

While prominent in the traditional literature, the localizationist and static view of brain
processing does not explain numerous observations of functional recovery following …

The purpose of surgery for brain tumors involving eloquent neural circuits is to maximize the
extent of resection while preserving an optimal quality of life. To this end, especially in …

Modern glioma surgery has evolved from the principal belief that safe, maximal tumor
resection improves symptom management, quality of life, progression-free survival, and …

Background Supratotal resection is advocated in lower-grade gliomas (LGGs) based on
theoretical advantages but with limited verification of functional risk and data on oncological …