Identification of key candidate genes for IgA nephropathy using machine learning and statistics based bioinformatics models
Abstract Immunoglobulin-A-nephropathy (IgAN) is a kidney disease caused by the
accumulation of IgAN deposits in the kidneys, which causes inflammation and damage to …
accumulation of IgAN deposits in the kidneys, which causes inflammation and damage to …
Transmembrane signaling molecules play a key role in the pathogenesis of IgA nephropathy: a weighted gene co-expression network analysis study
Abstract Background Immunoglobulin A nephropathy (IgAN) is one of the most common
primary glomerulonephritis and a serious health concern worldwide; though still the …
primary glomerulonephritis and a serious health concern worldwide; though still the …
[HTML][HTML] The efficacy of taking traditional Chinese medicine orally in renal interstitial fibrosis: a protocol for a systematic review and meta-analysis
G Yu, M Guo, J Zou, X Zhou, Y Ma - Medicine, 2020 - journals.lww.com
Background: By now, the incidence of chronic kidney disease (CKD) is increasing. The
development of various CKD is attributed to the continuous aggravation of renal interstitial …
development of various CKD is attributed to the continuous aggravation of renal interstitial …
Bioinformatics analysis reveals novel hub gene pathways associated with IgA nephropathy
X Jiang, Z Xu, Y Du, H Chen - European journal of medical research, 2020 - Springer
Abstract Background Immunoglobulin A nephropathy (IgAN) is the most common primary
glomerulopathy worldwide. However, the molecular events underlying IgAN remain to be …
glomerulopathy worldwide. However, the molecular events underlying IgAN remain to be …
Identification of hub genes and therapeutic agents for IgA nephropathy through bioinformatics analysis and experimental validation
M Xia, D Liu, H Liu, L Peng, D Yang, C Tang… - Frontiers in …, 2022 - frontiersin.org
Background IgA nephropathy (IgAN) is the most common primary glomerular disease and
the leading cause of the end-stage renal disease in the world. The pathogenesis of IgAN …
the leading cause of the end-stage renal disease in the world. The pathogenesis of IgAN …
[HTML][HTML] Identification of key biomarkers and immune infiltration in renal interstitial fibrosis
Z Hu, Y Liu, Y Zhu, H Cui, J Pan - Annals of Translational Medicine, 2022 - ncbi.nlm.nih.gov
Background Renal interstitial fibrosis (RIF) is the common final pathway that mediates
almost all progressive renal diseases. However, the underlying mechanisms of RIF have not …
almost all progressive renal diseases. However, the underlying mechanisms of RIF have not …
Klotho exerts protection in chronic kidney disease associated with regulating inflammatory response and lipid metabolism
J Liu, H Wang, Q Liu, S Long, Y Wu, N Wang, W Lin… - Cell & Bioscience, 2024 - Springer
Background The anti-aging protein Klotho plays a protective role in kidney disease, but its
potential as a biomarker for chronic kidney disease (CKD) is controversial. Additionally, the …
potential as a biomarker for chronic kidney disease (CKD) is controversial. Additionally, the …
Novel targets in renal fibrosis based on bioinformatic analysis
Y Yuan, X Xiong, L Li, P Luo - Frontiers in genetics, 2022 - frontiersin.org
Background: Renal fibrosis is a widely used pathological indicator of progressive chronic
kidney disease (CKD), and renal fibrosis mediates most progressive renal diseases as a …
kidney disease (CKD), and renal fibrosis mediates most progressive renal diseases as a …
Prediction of new candidate proteins and analysis of sub-modules and protein hubs associated with seed development in rice (Oryza sativa) using an ensemble …
MRP De Silva, J Weeraman, PC Fernando - bioRxiv, 2024 - biorxiv.org
Background Rice is a critical global food source, but it faces challenges due to nutritional
deficiencies and the pressures of a growing population. Understanding the molecular …
deficiencies and the pressures of a growing population. Understanding the molecular …
Screening for potential biological markers of chronic kidney disease based on WGCNA and machine learning
C Zhang, S Feng, H Li, S Wang - 2023 - researchsquare.com
Background: Chronic kidney disease (CKD) is defined as persistent urinary tract
abnormalities, structural abnormalities, or impaired excretory function of the kidneys, which …
abnormalities, structural abnormalities, or impaired excretory function of the kidneys, which …