3D printed microfluidics and microelectronics

RD Sochol, E Sweet, CC Glick, SY Wu, C Yang… - Microelectronic …, 2018 - Elsevier
Submillimeter-scale domains offer wide-ranging benefits for chemical and biological fields,
which have motivated researchers to develop a diversity of strategies for manufacturing …

Microfluidic systems for hydrodynamic trapping of cells and clusters

Q Luan, C Macaraniag, J Zhou, I Papautsky - Biomicrofluidics, 2020 - pubs.aip.org
Microfluidic devices have been widely applied to trapping and isolation of cells and clusters
for controllable intercellular environments and high-throughput analysis, triggering …

Finger-powered microfluidic systems using multilayer soft lithography and injection molding processes

K Iwai, KC Shih, X Lin, TA Brubaker, RD Sochol, L Lin - Lab on a Chip, 2014 - pubs.rsc.org
Point-of-care (POC) and disposable biomedical applications demand low-power microfluidic
systems with pumping components that provide controlled pressure sources. Unfortunately …

Microstructure-based techniques for single-cell manipulation and analysis

L Pang, J Ding, XX Liu, H Yuan, Y Ge, J Fan… - TrAC Trends in Analytical …, 2020 - Elsevier
Over the past few years, manipulating and analyzing methods based on single-cell level
have become frequently adopted to conduct the cell heterogeneity study (eg, differentiation …

A role for 3D printing in kidney-on-a-chip platforms

RD Sochol, NR Gupta, JV Bonventre - Current transplantation reports, 2016 - Springer
The advancement of “kidney-on-a-chip” platforms—submillimeter-scale fluidic systems
designed to recapitulate renal functions in vitro—directly impacts a wide range of biomedical …

Get to understand more from single-cells: current studies of microfluidic-based techniques for single-cell analysis

SJ Lo, DJ Yao - International journal of molecular sciences, 2015 - mdpi.com
This review describes the microfluidic techniques developed for the analysis of a single cell.
The characteristics of microfluidic (eg, little sample amount required, high-throughput …

A generalizable, tunable microfluidic platform for delivering fast temporally varying chemical signals to probe single-cell response dynamics

L Chingozha, M Zhan, C Zhu, H Lu - Analytical chemistry, 2014 - ACS Publications
Understanding how biological systems transduce dynamic, soluble chemical cues into
physiological processes requires robust experimental tools for generating diverse temporal …

Integration of a microfluidic chip with a size-based cell bandpass filter for reliable isolation of single cells

H Kim, S Lee, J Lee, J Kim - Lab on a Chip, 2015 - pubs.rsc.org
We report a simple, efficient microfluidic array system for reliable isolation of cells. A
microfluidic array chip, integrated with a size-based cell bandpass filter, provides the …

The latest advances in high content screening in microfluidic devices

W Liu, J Wang, H Qi, Q Jiao, L Wu… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction High content screening (HCS) is an important tool for drug screening. However,
the potential of HCS in the field of drug screening and synthetic biology is limited by …

A microfluidic-based dynamic microarray system with single-layer pneumatic valves for immobilization and selective retrieval of single microbeads

H Kim, J Kim - Microfluidics and nanofluidics, 2014 - Springer
A simple yet effective dynamic bead-based microarray is necessary for multiplexed high-
throughput screening applications in the fields of biology and chemistry. This paper …