Therapeutic Targeting of DNA Repair Pathways in Pediatric Extracranial Solid Tumors: Current State and Implications for Immunotherapy
SJ Zhao, D Prior, CM Heske, JC Vasquez - Cancers, 2024 - mdpi.com
Simple Summary Survival for many pediatric cancers has improved over recent decades.
However, for pediatric patients with solid tumors that fail to respond to standard therapies, or …
However, for pediatric patients with solid tumors that fail to respond to standard therapies, or …
A Phase II Trial of the WEE1 Inhibitor Adavosertib in SETD2-Altered Advanced Solid Tumor Malignancies (NCI 10170)
E Maldonado, WK Rathmell, GI Shapiro… - Cancer research …, 2024 - aacrjournals.org
We sought to evaluate the efficacy of WEE1 inhibitor adavosertib in patients with solid tumor
malignancies (cohort A) and clear cell renal cell carcinoma (ccRCC; cohort B) …
malignancies (cohort A) and clear cell renal cell carcinoma (ccRCC; cohort B) …